Cervical Rippening With Antiprogesterone in Midtrimester Abortions

Status Completed

Clinical Trial Summary

Induction of midtrimester abortion includes cervical ripening and then contraction to induce uterine evacuation. There are several protocols, but most of them include using prostaglandins (PG). The disadvantages of using PG include uncomfortable side effects and limits of using it for women after cesarean section. Mifepristone is an antiprogesterone drug and been used for induction of abortion in first and second trimesters abortions. The aim of this study is to explore the effectiveness of Mifepristone for cervical ripening before high dose Oxytocin drip.

Clinical Trial Description

The aim of this study is to explore the effectiveness of Mifepristone for cervical ripening before high dose Oxytocin drip in midtrimester abortions. After informed consent, all the women will be randomized for Mifepristone or placebo. 48 hours later, high dose oxytocin drip will be started and we will examine the success rate to induce abortion, the duration from starting oxytocin till evacuation of uterus and side effects. ;

Study Design

Related Conditions & MeSH terms

Abortion, Missed

Clinical Trial Details

NCT number	NCT00410345
Study type	Interventional
Source	Hadassah Medical Organization
Contact
Status	Completed
Phase	Phase 4
Start date	August 2004
Completion date	May 2008

View Details

See also
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