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Aberrant Crypt Foci clinical trials

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NCT ID: NCT00623883 Completed - Clinical trials for Colorectal Neoplasms

Colonoscopic Removal of Aberrant Crypt Foci: a Prospective, Randomized, Blinded Trial

Start date: January 1999
Phase: N/A
Study type: Interventional

We hypothesized that aberrant crypt foci (ACF) are precursors of colon cancer; their prevention would correlate with cancer risk and their elimination would reduce that risk. In this study we wished to (1) establish the feasibility of stain-enhanced magnification colonoscopy, (2) determine whether colorectal cancer is asociated with increased numbers of ACF, and (3) investigate the natural history of ACF and the durability of their elimination.

NCT ID: NCT00365209 Completed - Clinical trials for Tobacco Use Disorder

Phase II A Trial of Curcumin Among Patients With Prevalent Subclinical Neoplastic Lesions (Aberrant Crypt Foci)

Start date: October 2006
Phase: Phase 2
Study type: Interventional

Chemoprevention is the use of certain substances to keep cancer from forming, growing, or coming back. Curcumin is a compound found in plants that may prevent colon cancer from forming. This phase II trial is studying how well curcumin works in preventing colon cancer in smokers with aberrant crypt foci.

NCT ID: NCT00176618 Terminated - Aberrant Crypt Foci Clinical Trials

The Effects of Curcuminoids on Aberrant Crypt Foci in the Human Colon

Start date: April 2004
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the effectiveness of curcumin in reducing the number of aberrant crypt foci (ACF) in the colon.