Abdominal Surgery Clinical Trial
Official title:
Establishment and Research for Rapid Diagnosis of Postoperative Abdominal Infection Based on Metagenomic Sequencing
Verified date | November 2021 |
Source | Peking Union Medical College Hospital |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
This is a prospective and exploratory study, which utilizes non-targeted metagenomic next-generation sequencing (mNGS) detecting drain fluid from patients who are suspected of postoperative abdominal infection. This study aims to explore the clinical value of mNGS in the rapid diagnosis of postoperative abdominal infection, to refine the pathogenic bacteria spectrum, and to establish a novel procedure for postoperative abdominal infection diagnosis.
Status | Active, not recruiting |
Enrollment | 30 |
Est. completion date | December 31, 2022 |
Est. primary completion date | September 30, 2022 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: 1. Patients who receive abdominal operations with routinely abdominal drainage placement. 2. Abdominal infection is suspected by the clinicians, and one of the following conditions is met: 1. Temperature =38?; 2. One of the following laboratory indicators: WBC=10×10^9/L, PCT=0.5ng/ml, hsCRP=100mg/L. Exclusion Criteria: 1. Patients who are diagnosed with the abdominal infection before surgery. 2. Evidence of non-abdominal infection is clear and could explain the clinical symptoms. |
Country | Name | City | State |
---|---|---|---|
China | Peking Union Medical College Hospital | Beijing | Beijing |
Lead Sponsor | Collaborator |
---|---|
Peking Union Medical College Hospital |
China,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | The pathogenic spectrum of postoperative abdominal infection | Through study completion, an average of 1 year | ||
Secondary | Consistency between mNGS and conventional culture methods | Through study completion, an average of 1 year |
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