Effects of Exercise Modality on Abdominal Obesity and Health Risk Factors in Older Men and Women

Abdominal Obesity Clinical Trial

Official title:

Effects of Exercise Modality on Abdominal Obesity and Health Risk Factors in Older Men and Women

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00520858
• Other study ID #: Ross2002
• Status: Completed
• Phase: N/A
• First received: August 24, 2007
• Last updated: April 21, 2008
• Start date: September 2003

Study information

• Verified date: April 2008
• Source: Queen's University
• Contact: n/a
• Is FDA regulated: No
• Health authority: Canada: Canadian Institutes of Health Research
• Study type: Interventional

Clinical Trial Summary

The prevalence of abdominal obesity in the elderly is increasing at alarming rates and thus, requires immediate attention. By comparison to younger adults, obesity reduction in the elderly presents a unique challenge and requires an innovative approach. We propose a novel approach to investigate the effects of different exercise types as independent treatment strategies for the reduction of obesity and related health risk factors in older men and women. We propose that exercise without caloric restriction will be associated with modest weight loss (3-5%), that in turn will be associated with significant reduction in abdominal obesity, insulin resistance, and a corresponding increase in skeletal muscle mass and function. We will determine the separate effects of resistance and aerobic exercise on these primary outcome variables, and, whether a treatment strategy that combines the two is optimal.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 145
• Gender: Both
• Age group: 65 Years to 80 Years

Eligibility

Inclusion Criteria:

• Men and women between 65 and 80 years of age.

• Men and women are self-sufficient, sedentary, abdominally obese (BMI between 27 and 34.9 kg/m2; waist circumference greater than 88 cm in women and 102 cm in men), weight stable (± 2 kg) for 6 months prior to the beginning of the study, be non-smokers, and not diabetic.

• We will study elderly women who are not taking hormone replacement therapy to create a homogeneous population in whom the effect of exercise on the principal outcome variables can be evaluated with minimal confounding.

Exclusion Criteria:

• Smokers and diabetics.

• Women taking hormone replacement therapy.

Study Design

Intervention Model: Parallel Assignment, Masking: Single Blind (Investigator), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Abdominal Obesity
• Obesity
• Obesity, Abdominal

Intervention

Other:
• Resistance Exercise (RE)

• Aerobic Exercise (AE)

• Resistance and Aerobic Exercise (RAE)

Locations

Country	Name	City	State
Canada	Queen's University	Kingston	Ontario

Sponsors (2)

Lead Sponsor	Collaborator
Queen's University	Canadian Institutes of Health Research (CIHR)

Country where clinical trial is conducted

Canada, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Abdominal obesity		6 months
Secondary	Insulin Resistance		6 Months