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Abdominal Neoplasms clinical trials

View clinical trials related to Abdominal Neoplasms.

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NCT ID: NCT03460561 Completed - Abdominal Cancer Clinical Trials

Peri-operative Rectus Sheath Block Versus TEA Abdominal Surgeries

Start date: August 1, 2016
Phase: Phase 3
Study type: Interventional

Thoracic epidural analgesia (TEA) can be considered the gold standard for postoperative analgesia in major abdominal surgeries, as proved by a lot of number of systematic reviews and meta-analyses have demonstrated that TEA was associated with superior postoperative analgesia, better patients' outcomes, reducing (systemic opiate requirements, ileus and pulmonary complications). The rectus sheath block (RSB) is effective for the surgeries that necessitated midline abdominal incisions as local anesthetics instillation will be within the posterior rectus sheath bilaterally providing intense analgesia for the middle anterior wall from the xiphoid process to the symphysis pubis in adults.

NCT ID: NCT03165383 Completed - Abdominal Cancer Clinical Trials

The Analgesic Efficacy of Ultrasound Guided Transversus Abdominal Plane Block After Abdominal Cancer Surgeries

TAP
Start date: February 11, 2013
Phase: N/A
Study type: Interventional

Effective postoperative pain control results in decreased cardiac and pulmonary complications, patient satisfaction and early mobilization. A prospective, randomized comparative study was done of analgesic efficacy, opioid requirement and side effects in patients undergoing lower abdominal cancer surgeries. In Study Group Ultrasound guided Transversus Abdominis Plane (TAP) block was given and control Group no TAP block was given. Patient controlled analgesia (PCA) with intravenous morphine was given to both group patients, and total good PCA demands in both the groups was studied.

NCT ID: NCT03060070 Completed - Clinical trials for Postoperative Analgesia

Ketamine Versus Dexmedetomidine With Local Anesthetic in TAP Block

Start date: March 10, 2017
Phase: Phase 2/Phase 3
Study type: Interventional

Comparing the analgesic effects of ketamine and dexmedetomidine when added to local anesthetic in TAP block for postoperative analgesia after lower abdominal cancer surgery.

NCT ID: NCT03002909 Completed - Abdominal Neoplasms Clinical Trials

Continuous Pre-peritoneal Wound Infiltration Versus Epidural Analgesia in Cancer Surgery

Start date: January 2017
Phase: N/A
Study type: Interventional

the investigators aim is to investigate the effect of continuous preperitoneal bupivacaine wound infiltration versus epidural analgesia on the inflammatory cytokines response following radical cytectomy

NCT ID: NCT02927379 Completed - Abdominal Cancer Clinical Trials

Effect of Wound Infiltration by Ketamine Versus Dexmedetomidine Added to Bupivacaine on Surgical Stress

Start date: June 2016
Phase: Phase 3
Study type: Interventional

This study aims to compare the effects of local wound infiltration with ketamine versus dexmedetomidine when added to bupivacaine on stress response and postoperative pain in lower abdominal cancer surgery.

NCT ID: NCT02653469 Completed - Clinical trials for Gynecologic Neoplasms

Augmented Pulse Pressure Variation to Predict Fluid Responsiveness in Open Laparotomy

Start date: September 2015
Phase: N/A
Study type: Observational

Pulse pressure variation (PPV) is a well-known and widely used dynamic preload indicator based on heart-lung interaction to predict fluid responsiveness. Generally, patients are considered to be fluid-responsive when the PPV value larger than 11-13%. However, several previous researches demonstrated that there is a zone of uncertainty (grey zone) in PPV. To predict fluid-responsiveness accurately in the patients with PPV within grey zone (9-13%), the investigators would evaluate the augmented PPV using augmented ventilation.

NCT ID: NCT02566096 Completed - Abdominal Cancer Clinical Trials

Efficacy of Transverses Abdominis -Plane Block With Bupivacaine Versus Bupivacaine With Morphine Postoperatively

Start date: September 2015
Phase: Phase 4
Study type: Interventional

This study aims to compare the analgesic efficacy of transversus abdominis-plane block with bupivicaine versus bupivacaine with morphine in patients undergoing major abdominal cancer surgery.

NCT ID: NCT02307253 Completed - Abdominal Neoplasms Clinical Trials

EUS GUIDED Transduodenal Biopsy Using the 19G Flex

NIFLEX
Start date: June 2013
Phase: N/A
Study type: Interventional

This study evaluates the feasibility, safety and accuracy of a 19 gauge (19G) needle in nitinol in the performance of endoscopic ultrasound (EUS) guided transduodenal biopsy for the acquisition of samples for histologic analysis. Patients with lesions that can be approached only from the duodenum will be prospectively enrolled.

NCT ID: NCT02197988 Completed - Surgery Clinical Trials

TAP Versus Thoracic Epidural in Major Abdominal Resections

Start date: December 3, 2013
Phase: N/A
Study type: Interventional

The purpose of this study is to compare two standard methods of pain control management used at Spectrum Health for patients undergoing major surgery. The two methods being compared are the thoracic epidural and the TAP block. The thoracic epidural method involves medication being given through a patient's back and the TAP block involves medication being given through a patient's abdomen (belly). The investigators will compare side effects experienced by the patients that take part in this study, including a change in blood pressure, as well as the patients' opinions about their pain management experience after surgery.

NCT ID: NCT01399814 Completed - Surgery Clinical Trials

Restricted Intravenous Fluid Regime Effects on Immunological Indicators of Elderly Patients Operated for Abdominal Cancer

Start date: May 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to find out whether perioperative fluid restriction influence on postoperative immunological function. And discuss the probable mechanism that fluid restriction regime effect on clinical data.