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Abdominal Neoplasms clinical trials

View clinical trials related to Abdominal Neoplasms.

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NCT ID: NCT03879395 Completed - Melanoma Stage Iv Clinical Trials

Surgery for Gastrointestinal Metastases of Malignant Melanoma - a Single Center Retrospective Cohort Study

Start date: January 1, 2010
Study type: Observational

The aim is to conduct a single centre retrospective study of all patients with stage IV melanoma that underwent surgery for metastases at Sahlgrenska University Hospital between 2010-01-01 and 2018-12-31. Pre- and postoperative data will be collected from digital medical records, the Swedish Cancer Registry, the Swedish Cause of Death Register as well as from the national Swedish cancer patient database (INCA). If needed, patient records will be collected from other hospitals. Results will be presented in written format as a summary and analysis of the characteristics of the cases operated on during the inclusion period. The aim is to identify predictive and prognostic factors for outcome and complications in the surgical treatment of stage IV metastatic melanoma.

NCT ID: NCT03775005 Recruiting - Palliative Care Clinical Trials

Short Course Radiation Therapy in Palliative Treatment of Abdominal Cancer

Start date: November 8, 2017
Phase: N/A
Study type: Interventional

Aim of the study is to assess efficacy of a short course radiation treatment in patients with symptomatic abdominal malignant lesions

NCT ID: NCT03762785 Recruiting - Abdominal Cancer Clinical Trials

Pharmacokinetics and Dynamics of Nebulized Dexmedetomidine

Start date: December 10, 2018
Phase: Phase 1/Phase 2
Study type: Interventional

the aim of this study is to study the pharmacokinetics and dynamics of nebulized dexmetedomidine in children undergoing major abdominal cancer surgery.

NCT ID: NCT03513757 Recruiting - Headache Clinical Trials

Dexmedetomidine and Propofol for Pediatric MRI Sedation

Start date: March 4, 2018
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare the results of combining two anesthetic medications (dexmedetomidine and propofol) in low doses with a standard dose of a single drug that is commonly used to provide sedation/anesthesia for MRI studies in young children (propofol). The drugs used for the MRI scan in this study will be chosen randomly. Half the patients will receive small doses of propofol and dexmedetomidine. The other half will receive propofol administered constantly throughout the scan. Other drugs that may be used include sevoflurane and nitrous oxide at the start of the sedation (for placing an intravenous), lidocaine (to reduce the pain of propofol injection) and glycopyrrolate (to prevent the heart rate from decreasing too low. The investigators will record 5 additional blood pressures and heart rates. If additional medications are required to complete the scan, the investigators will administer whatever is necessary. At the end of the study, the investigators will have an observer record the time it takes for participants to spontaneously open eyes , to be able to drink liquids and/or eat and to behave as before the study. Also, it is very important that the investigators find out from participants about changes in behavior, or if eating or sleeping habits were unusual following completion of the study. For that reason, the investigators will call participants in a day or so following the MRI scan. The investigators expect to recruit 70 children between the ages of 12 and 72 months for the study and hope to have the study completed in December 2018.

NCT ID: NCT03460561 Completed - Abdominal Cancer Clinical Trials

Peri-operative Rectus Sheath Block Versus TEA Abdominal Surgeries

Start date: August 1, 2016
Phase: Phase 3
Study type: Interventional

Thoracic epidural analgesia (TEA) can be considered the gold standard for postoperative analgesia in major abdominal surgeries, as proved by a lot of number of systematic reviews and meta-analyses have demonstrated that TEA was associated with superior postoperative analgesia, better patients' outcomes, reducing (systemic opiate requirements, ileus and pulmonary complications). The rectus sheath block (RSB) is effective for the surgeries that necessitated midline abdominal incisions as local anesthetics instillation will be within the posterior rectus sheath bilaterally providing intense analgesia for the middle anterior wall from the xiphoid process to the symphysis pubis in adults.

NCT ID: NCT03459417 Enrolling by invitation - Abdominal Pain Clinical Trials

Safety and Efficacy of Intrathecally Administered Magnesium Sulfate

Start date: January 1, 2018
Phase: Phase 3
Study type: Interventional

Magnesium sulfate safety profile has been documented by histopathological analysis in experimental studies. magnesium sulfate added to local anesthetics decrease postoperative opioid requirements.

NCT ID: NCT03453424 Active, not recruiting - Abdominal Pain Clinical Trials

Analgesic Efficacy of Dexmedetomidine Added to Fentanyl in PCEA

Start date: June 30, 2017
Phase: Phase 3
Study type: Interventional

Dexmedetomidine if add to patient controlled epidural analgesia for patients undergoing major abdominal cancer surgery may improve its effects.

NCT ID: NCT03221335 Recruiting - Clinical trials for Digestive System Neoplasms

EUS-guided RFA for Solid Abdominal Neoplasms

Start date: May 2016
Phase: N/A
Study type: Interventional

Radiofrequency ablation has been used for treatment of solid neoplasms of the liver, lung, kidney and adrenal. Recently, EUS-guided RFA has become available and the device allows EUS-guided treatment of solid abdominal neoplasms. The procedure has been shown to be feasible in the porcine pancreas and was used to treat small groups of patients that are not suitable for surgery suffering from pancreatic cancers. The aim of the current study is to perform a multi-center prospective study on EUS-guided radiofrequency ablation (RFA) of solid abdominal neoplasms. The hypothesis is that EUS-guided RFA is safe, feasible and effective for treating solid abdominal neoplasms.

NCT ID: NCT03169439 Not yet recruiting - Oncology Clinical Trials

Irreversible Electroporation for Treatment of Solid Abdominal Tumors

Start date: July 1, 2017
Phase: N/A
Study type: Interventional

Irreversible electroporation (IRE) is a novel non-thermal ablation modality with promise for revolutionizing the treatment for local solid tumors. With the growing demand for alternative and less invasive treatments for localized tumors, the investigators have seen the development and investigation of several tissue ablation modalities, including radiofrequency ablation (RFA), microwave ablation, and cryoablation. Although these modalities have been efficacious, they have some disadvantages owing to their reliance on thermal energy for creating cell death.

NCT ID: NCT03165383 Completed - Abdominal Cancer Clinical Trials

The Analgesic Efficacy of Ultrasound Guided Transversus Abdominal Plane Block After Abdominal Cancer Surgeries

Start date: February 11, 2013
Phase: N/A
Study type: Interventional

Effective postoperative pain control results in decreased cardiac and pulmonary complications, patient satisfaction and early mobilization. A prospective, randomized comparative study was done of analgesic efficacy, opioid requirement and side effects in patients undergoing lower abdominal cancer surgeries. In Study Group Ultrasound guided Transversus Abdominis Plane (TAP) block was given and control Group no TAP block was given. Patient controlled analgesia (PCA) with intravenous morphine was given to both group patients, and total good PCA demands in both the groups was studied.