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Abdominal Neoplasms clinical trials

View clinical trials related to Abdominal Neoplasms.

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NCT ID: NCT06430112 Recruiting - Clinical trials for Postoperative Analgesia

Liposomal Bupivacaine vs Ropivacaine for TAPBs

Start date: November 1, 2023
Phase: Phase 3
Study type: Interventional

Few studies have compared the efficacy of ultrasound (US)-guided TAP blocks with Liposomal bupivacaine(LB) versus ropivacaine in reducing postoperative opioid usage in patients undergoing laparoscopic lower abdominal tumor Resection. Therefore, we are conducting this prospective, randomized controlled trial to compare the postoperative analgesic effects of LB and ropivacaine for TAP blocks among patients undergoing laparoscopic colorectal procedures.

NCT ID: NCT06301789 Not yet recruiting - Clinical trials for QLB in Lower Abdominal Cancer Surgeries as a Post Operative Analgesia

Role of Magnesium Sulphate as an Adjuvant to Bupivacaine in U.S Guided Quadratus Lumborum Block in Lower Abdominal Cancer Surgeries

Start date: April 2024
Phase: N/A
Study type: Interventional

The aim of this study is to assess the efficacy of Mg sulfate ( 10% ) as an adjuvant to Bupivacain ( 0.25 % ) in an U.S guided QLB for postoperative analgesia and postoperative Morphine consumption in lower abdominal cancer surgeries.

NCT ID: NCT06293391 Completed - Blood Pressure Clinical Trials

The Effect of Patient Position Changes on Advanced Cardiac Indices in Cancer Surgery

Start date: February 1, 2023
Phase:
Study type: Observational

Esophageal Doppler Monitoring (Deltex CardioQ Esophageal Doppler Monitor, ODM) is used to manage patients' fluid therapy by non-invasively measuring continuous cardiac output with an esophageal probe. The aim of this study was to compare the effects of patient position changes on cardiac indices and vital signs in patients who underwent major abdominal cancer surgery with laparoscopic and open surgery using ODM.

NCT ID: NCT06276738 Not yet recruiting - Pancreatic Cancer Clinical Trials

The LINFU® U.S. Registry in Patients With Clinical Signs and/or Symptoms of Disease

Start date: June 30, 2024
Phase:
Study type: Observational [Patient Registry]

Evaluate LINFU® in patients who exhibit signs or symptoms (i.e. jaundice, abdominal pain, weight loss, nausea and vomiting etc.) suggestive of pancreatic cancer (PDAC) or have evidence of imaging studies suggestive of PDAC.

NCT ID: NCT06265948 Not yet recruiting - Abdominal Cancer Clinical Trials

Comparsion Between Intravenous Infusion of Ketofol and Inhalational Anasthetics in Abdominal Cancer Surgeries for Post Operative Analgesia

Start date: March 2024
Phase:
Study type: Observational

( post operative pain between intravenous infusion ketofol and standard inhalational general anesthesia in abdominal cancer surgeries )

NCT ID: NCT06232577 Recruiting - Clinical trials for Intra-abdominal Cancer

5x-Multiplier vs 3-Tier Model for Discharge Opioid Prescriptions After Intra-abdominal Cancer Surgery: A Randomized Clinical Trial

Start date: March 27, 2024
Phase: Phase 2
Study type: Interventional

To compare 2 different models for prescribing opioid pain medication to provide better pain control to participants with an abdominal cancer who are having surgery.

NCT ID: NCT06212570 Not yet recruiting - Abdominal Neoplasm Clinical Trials

KeyScope Study in Uganda

Start date: January 1, 2025
Phase: N/A
Study type: Interventional

KeyScope and KeyLoop (collectively called KeySuite) are laparoscopic prototypes that the investigators have designed for the resources, needs and challenges of low- and middle- income countries (LMICs). KeyScope is a laparoscope that plugs into a laptop computer to display images during surgery. It links to a telementoring application so that experienced surgeons can mentor surgeons in capacity-building partnerships. KeyLoop is a laparoscopic retractor that lifts the abdominal wall during surgery, obviating the need for a constant power supply and medical-grade carbon dioxide. The investigators will perform a clinical First-in-Human study at the Uganda Cancer Institute. Ugandan surgeons will use the KeySuite devices to perform biopsies of intra-abdominal tumors.

NCT ID: NCT06042023 Recruiting - Surgery Clinical Trials

Remote Patient Monitoring for Preoperative Risk Assessment

REMOTES
Start date: December 19, 2022
Phase: N/A
Study type: Interventional

Preoperative risk assessment (an evaluation of overall health before surgery) is important to determine the overall risk of mortality and complications for patients undergoing major abdominal surgery to allow the appropriate allocation of sparse hospital resources. The current gold standard for preoperative assessment is cardiopulmonary exercise testing (CPET). CPET is, however, not available in all centres that perform major surgery, it is a costly test, and therefore only high-risk patients are tested. Finding new ways of conducting preoperative assessment could improve overall surgical safety, patient experience and reduce cost. The preoperative use of remote vital signs monitoring can provide important information about the patients' fitness and overall health and may be used for preoperative assessment. This study will use a remote monitoring patch to monitor patients' vital signs before surgery. The aim is to evaluate the utility and patient acceptability of the remote monitoring system and the feasibility of a randomised controlled trial of this type of assessment. Additionally, the study will assess the correlation between the data captured by the remote monitoring system and the CPET results to evaluate the remote monitoring system's ability to predict risk of surgery. The study will take place in Leeds Teaching hospitals. Adult patients undergoing major abdominal surgery that require CPET before surgery are eligible. Participants will be monitored at home with the patch monitor for 3-5 days before surgery, in addition to their planned preoperative assessment. During remote monitoring, patients will be asked to complete questionnaires on their general health and experience using the patch paired with the mobile phone as part of the monitoring system. Clinical data from the electronic hospital records and general practitioner records available on the trust system will then be collected after surgery to assess complications and calculate risk scores.

NCT ID: NCT05637359 Completed - Abdominal Cancer Clinical Trials

Tracked Ultrasound for Patient Registration in Surgical Navigation During Abdominal Cancer Surgery

Start date: July 13, 2020
Phase:
Study type: Observational [Patient Registry]

The goal of this observational pilot study is to evaluate the feasibility and accuracy of tracked ultrasound registration on patients undergoing abdominal cancer navigation surgery. The main research question is: Could tracked ultrasound be applied as an alternative to standard CBCT scanning in surgical navigation? Participants will undergo tracked ultrasound measurements of the pelvic bone on the operating room after patient anesthesia and before surgical incision.

NCT ID: NCT05617755 Recruiting - Ovarian Neoplasms Clinical Trials

AB-1015, an Integrated Circuit T (ICT) Cell Therapy in Patients With Platinum Resistant Epithelial Ovarian Cancer

Start date: November 29, 2022
Phase: Phase 1
Study type: Interventional

This is a multi-center, open-label phase 1 dose escalation trial that uses a modified 3+3 design to identify a recommended phase 2 dose (RP2D) of AB-1015 cell product. Backfill cohorts will enroll additional subjects at doses deemed to be safe for a total enrollment of up to 12 subjects per each backfill cohort on the protocol.