Contrast Enhanced Ultrasound, Endoleak Detection Following EVAR v1.3

Status Completed

Clinical Trial Summary

A single site cross-sectional comparison of paired diagnostic imaging modalities. This study will show the sensitivity and specificity of CEUS in detecting the various types of endoleaks, in comparison to tCTA, following EVAR. It will collect data to allow comparison of diagnostic accuracy across modalities including CDU, CEUS and tCTA. It will collect time taken to perform the various types of scan, to allow healthcare costs to be calculated for each imaging modality.

Clinical Trial Description

This study will show the sensitivity and specificity of CEUS in detecting the various types of endoleaks, in comparison to tCTA, following EVAR. It will collect data to allow comparison of diagnostic accuracy across modalities including CDU, CEUS and tCTA. It will collect time taken to perform the various types of scan, to allow healthcare costs to be calculated for each imaging modality. Collected data will be analysed regarding two novel hypothesised methods of using CEUS information: The first is recording temporal delay between contrast in graft and contrast in endoleak to define endoleak type. Potentially this could be used as a faster method of defining endoleak type in a surveillance programme. The second is to identify/refute correlation between CEUS contrast to appear in endoleak vs tCTA contrast to appear in endoleak. If an association can be established, CEUS timings could potentially then be used to time 'standard' CTA phases to improve CTAs diagnostic accuracy. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02688751
Study type	Observational
Source	Liverpool University Hospitals NHS Foundation Trust
Contact
Status	Completed
Phase
Start date	January 20, 2016
Completion date	March 20, 2018

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