Biomarkers of Aneurysm Wall Strength

Status Recruiting

Clinical Trial Summary

The purpose of this study is to identify possible in vivo biochemical and biological markers related to aortic wall strength.

Clinical Trial Description

Rupture of an Abdominal Aortic Aneurysm (AAA) is potentially lethal. prophylactic surgical repair is therefore warranted when the risk of rupture exceeds the risk of complications following surgery. Aneurysm rupture occurs when the forces (stress) acting on the aneurysm wall surpass aneurysm wall strength. Information on both wall stress and strength might therefore improve rupture risk assessment and patient selection for prophylactic repair. Although aneurysm wall stress calculations are possible, no in vivo method exists to determine aneurysm wall strength. This study was designed to identify possible biomarkers of aneurysm wall strength ;

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00740740
Study type	Observational
Source	Radboud University
Contact	Maarten Truijers, MD
Phone	0031-24-3615333
Email	M.Truijers@chir.umcn.nl
Status	Recruiting
Phase	N/A
Start date	June 2007
Completion date	January 2010

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