Use of Iterative Reconstruction Method in Ultralow-dose CT for Follow-up of Patients With Intraabdominal Abscess: Comparison With Standard Dose CT

Abdominal Abscess Clinical Trial

Official title:

Use of Iterative Reconstruction Method in Ultralow-dose CT for Follow-up of Patients With Intraabdominal Abscess: Comparison With Standard Dose CT

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03681665
• Other study ID #: 4-2015-0413
• Status: Completed
• Start date: June 29, 2018
• Est. completion date: March 18, 2019

Study information

• Verified date: September 2020
• Source: Yonsei University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Increasing radiation exposure by medical examinations is getting more concerns. For optimal medical imaging, reducing radiation exposure with preservation image quality is important. One of the solutions is use of iterative recontruction of CT examination. In this study, the investigators aimed to investigate the clinical feasibility of ultralow dose abdominopelvic CT with iterative reconstruction in patients with intraabdominal abscess. Patients with intrabdominal abscess usually undergo multiple CT examinations to evaluate treatment response. Therefore, ultralow dose CT can reduce unnecessary radiation exposure in these patients.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 20
• Est. completion date: March 18, 2019
• Est. primary completion date: March 18, 2019
• Accepts healthy volunteers: No
• Gender: All
• Age group: 20 Years to 100 Years

Eligibility

Inclusion Criteria:

1. patients who underwent standard dose CT for suspected intraabdominal abscess

2. patients who need follow-up CT to evaluate treatment response of abscess 3) Adult patient, 4) patients who agreed this study protocol

Exclusion Criteria:

1. pregnancy

2. patients with poor renal function (GFR < 30 mL/min/1/73m2)

3. Patients who have allergy to CT contrast media

4. Patients who are not cooperative (e.g., dementia)

Related Conditions & MeSH terms

• Abdominal Abscess
• Abscess

Intervention

Other:
• ultralow dose abdominopelvic CT
In the patient cohort with abdominal abscess, ultralow dose abdominopelvic CT will be performed as a follow-up protocol. Ultralow dose CT has approximately 80~90% reduced radiation dose compared to standard dose CT.

Locations

Country	Name	City	State
Korea, Republic of	Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine	Seoul

Sponsors (1)

Lead Sponsor	Collaborator
Yonsei University

Country where clinical trial is conducted

Korea, Republic of, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Score of subjective image quality of CT image	Score of subjective image quality of CT images consists of overall subjective image quality, noise, diagnostic ability, and artifact.	1 month
Secondary	Effective radiation dose: CTDIvol(volume CT dose index), DLP(dose length product), effective dose(DLPx0.015)	Effective radiation dose between standard dose CT and ultra-low dose CT will be compared	1 month