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Wounds and Injuries clinical trials

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NCT ID: NCT05507437 Completed - Clinical trials for Acute Kidney Injury Due to Sepsis

Pharmacokinetics and Safety of TIN816 in Patients With Sepsis-associated Acute Kidney Injury

Start date: November 22, 2022
Phase: Phase 2
Study type: Interventional

The purpose of this study is to characterize the pharmacokinetic (PK) and pharmacodynamic (PD) profile and to evaluate the safety and tolerability of TIN816 in hospitalized adult participants in an intensive care setting with a diagnosis of sepsis-associated acute kidney injury (SA-AKI).

NCT ID: NCT05500131 Completed - Knee Injuries Clinical Trials

The Association Between Restricted Ankle Joint Dorsiflexion and Dynamic Knee Valgus

TOBROD
Start date: October 1, 2018
Phase:
Study type: Observational

The purpose of this study was to analyze if a low ankle dorsiflexion range is associate with dynamic knee valgus in youth basketball players.

NCT ID: NCT05499104 Completed - Pain Management Clinical Trials

A Trial Comparing a Cellulose Dressing to Two Standard of Care Dressings in Treating Split Thickness Donor Sites in Burn and Wound Patients.

Start date: July 16, 2021
Phase: Phase 3
Study type: Interventional

This is a three arm study, comparing the Novadress, Mepilex Ag, and Xeroform Occlusive dressings for healing, drainage, and pain management. NovaDress is constructed of pure cellulose derived from tree pulp. Mepilex Ag is a antimicrobial foam dressing that absorbs low to moderate exudate and maintains a moist wound environment. Xeroform Occlusive Dressing is a fine-mesh gauze impregnated with a petrolatum blend, 3% bismuth tribromophenate.

NCT ID: NCT05483647 Completed - Chronic Pain Clinical Trials

ERECTOR SPINE PLANE BLOCK VERSUS LOCAL INFILTRATION ANAESTHESIA FOR TRANSFORAMINAL PERCUTANEOUS ENDOSCOPIC DISCECTOMY

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

The main aim of our study was to test the hypothesis that Erector spine plane block (ESP) with sedation will provide the similar employment of fentanyl and propofol during surgery as an infiltrative local anaesthesia with sedation. The primary endpoint was the quantity of fentanyl and propofol during surgery.

NCT ID: NCT05479227 Completed - Bile Duct Injury Clinical Trials

Bile Duct Injuries During Laparoscopic Cholecystectomies: An 11-year Population-based Study

Start date: June 1, 2019
Phase:
Study type: Observational

The aim of this retrospective study is to review the annual incidence, management, and outcomes of bile duct injuries (BDI) during laparoscopic cholecystectomy (LC) in a population-based cohort during 2008-2018 in Estonia.

NCT ID: NCT05475418 Completed - Wounds and Injuries Clinical Trials

Pilot Study of Human Adipose Tissue Derived Exosomes Promoting Wound Healing

Start date: August 5, 2022
Phase: N/A
Study type: Interventional

This study is a one-arm pilot study. All patients were recruited on an outpatient basis. After screening visits and informed consent was obtained, debridement and photography were performed on the patient's wound surface, and the wound area was measured. Patients in the intervention group were then provided with adipose tissue exosome dressings.200-300ml of the subject adipose tissue before centrifugation was collected, and the extracellular vesicles were retained after tissue homogenate and filter screening. The extracellular vesicles were mixed with sterile hydrogel and applied directly to the wound surface, and the wound was covered with an inert protective dressing.

NCT ID: NCT05475093 Completed - Clinical trials for Micturition Disorder

Impact Evaluation of Different Micturition Modes on Patients With Medullar Injury of Quality of Life and Their Occupations

URO-ActSCi
Start date: July 22, 2022
Phase:
Study type: Observational

The primary objective of the study is to analysis the personal determination factors (age, sex, stage of injury, pain, urinary continence and durations of spinal cord injury) and environmental determination factors (need for medical devices, nurse care and adaptation of accommodations) which affect the quality of life and their occupations on patients with medullar injury.

NCT ID: NCT05471297 Completed - Injuries Clinical Trials

Loads, Injuries and Illnesses Among Elite Handball Players

PPDC-2022
Start date: July 20, 2022
Phase:
Study type: Observational

Primary goal of the research is to determine whether injury/illness occurrence is influenced by the academic, training and competition loads, as well as the overall load (sum of academic/work, training and competition loads) in elite handball athletes To examine whether subjective measures of perceived overall stress correlate with objectively measured levels of stress. Determine the benefits of certain biomarkers to monitor stress, load and injury/illness occurrence in athletes.

NCT ID: NCT05469139 Completed - Clinical trials for Extracorporeal Membrane Oxygenation Complication

Assessing Brain Injury Using Portable Magnetic Resonance Imaging (MRI)

SAFE MRI
Start date: December 10, 2021
Phase:
Study type: Observational

This study aims to assess the feasibility of assessing acute brain injury using a portable low field MRI in patients on ECMO.

NCT ID: NCT05465083 Completed - Clinical trials for Acute Hypoxemic Respiratory Failure

Feasibility of Transvenous Phrenic Nerve Stimulation for Diaphragm Protection in Acute Respiratory Failure

STIMULUS
Start date: February 4, 2023
Phase: N/A
Study type: Interventional

This is a single-center proof-of-concept clinical trial designed to establish the feasibility of transvenous phrenic-nerve stimulation (PNS) to maintain diaphragm activation over the first 24 hours and for up to seven days of mechanical ventilation in patients who are likely to require more than 48 hours of invasive mechanical ventilation.