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Wound Infection clinical trials

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NCT ID: NCT00550290 Completed - Wound Infection Clinical Trials

Prophylactic Antibiotics for Prevention of Wound Complications Following Vulvectomy

Start date: October 2007
Phase: Phase 4
Study type: Interventional

This randomized prospective study will specifically investigate the efficacy of a 24 hour post-operative course of broad-spectrum prophylactic antibiotics - namely Cefazolin - in preventing wound infection and wound breakdown following vulvectomy.

NCT ID: NCT00530400 Completed - Clinical trials for Surgical Wound Infection

Study of the Efficacy of Preoperative Cefuroxime Prophylaxis to Prevent Surgical Site Infection in Herniated Disk Surgery

Start date: April 1994
Phase: Phase 4
Study type: Interventional

The purpose of the study is to determine whether a single, pre-operative dose of cefuroxime is effective in preventing surgical site infection in patients undergoing surgery for herniated disk

NCT ID: NCT00528008 Terminated - Wound Infection Clinical Trials

A Comparison of Surgical Preparations and Wound Infection Rates for Elective Cesarean Sections

Start date: December 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study is to find out if chlorhexidine gluconate solution is better at reducing the rate of wound infection after cesarean section compared to povidone-iodine.

NCT ID: NCT00508053 Completed - Wound Infection Clinical Trials

When Closing Midline Incisions, do Small Stitches Reduce the Risk for Incisional Hernia, Wound Infection or Dehiscence?

Start date: January 2001
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether a technique using very small stitches when closing a midline incision can reduce the risk for wound complications such as incisional hernia, infection or dehiscence.

NCT ID: NCT00500669 Terminated - Recurrence Clinical Trials

A Randomised Study to Assess Betadine in the Groin Wound of Patients Undergoing Primary Varicose Vein Surgery

Start date: June 2004
Phase: Phase 3
Study type: Interventional

To investigate whether Betadine can reduce infection rates and recurrence rates following varicose veins surgery in a randomized double blind placebo controlled study.

NCT ID: NCT00484055 Completed - Clinical trials for Postoperative Wound Infection

Local Collagen-Gentamicin and Extra Fixation of the Sternum for Prevention of Sternal Wound Infection in Cardiac Surgery

LOGIX
Start date: January 2007
Phase: N/A
Study type: Interventional

The aim of the present study is to evaluate a new technique for prevention of sternal wound infection consisting of local application of collagen-gentamicin in addition to routine i.v. antibiotic prophylaxis. The technique has been evaluated in a previous randomised study. The aim of the present study is to evaluate the technique after it has been introduced in clinical practise to monitor the bacterial antibiotic susceptibility and to verify that the suggested reduction in sternal wound infection still exits.

NCT ID: NCT00463762 Withdrawn - Appendicitis Clinical Trials

Cefoperazone/Sulbactam In The Treatment Of Serious Intra-Abdominal And Hepatobiliary Infections.

Start date: May 2007
Phase: Phase 4
Study type: Observational

The primary objective is to collect data on treatment outcomes (clinical and microbiological cure), safety and tolerability of treatment with cefoperazone/sulbactam in patients with serious intra-abdominal and hepatobiliary infections in Slovakia.

NCT ID: NCT00402727 Completed - Diabetic Foot Clinical Trials

Comparison of Sequential IV/PO Moxifloxacin With IV Piperacillin/Tazobactam Followed by PO Amoxicillin/Clavulanic Acid in Patients With a Complicated Skin and Skin Structure Infection

Start date: September 2006
Phase: Phase 3
Study type: Interventional

Patients, who are considered suitable by their physicians to take part in this research, will have a physical examination (including an Electrocardiogram (ECG)), blood and urine samples taken, as well as a sample of the secretions or tissue around their infection site. In addition, the site of the infection will be photographed. The patients will be randomly assigned one of the treatments: intravenous (IV)/per oral (PO) moxifloxacin (drug under evaluation) or IV piperacillin/tazobactam followed by PO amoxicillin/clavulanic acid (i.e., one of the reference treatments for this kind of infection). The maximum treatment duration will be 21 days, and the minimum will be 7 days. During the hospitalization, the patients will have a physical examination every day. On Day 3-5 during therapy as well as at the end of treatment, the patients will have repeated examinations. These tests and evaluations will be repeated 14 to 28 days after the end of treatment. During this visit, blood and urine samples will be taken only if judged necessary by the physicians.

NCT ID: NCT00386477 Terminated - Cesarean Section Clinical Trials

Vaginal Cleansing at Cesarean Delivery to Reduce Infection: A Randomized, Controlled Trial

Start date: September 2006
Phase: N/A
Study type: Interventional

The objective of the project is to find out whether cleansing the vagina before a cesarean delivery decreases the risk of complications and infections after having the baby. If this is the case, cleansing the vagina before cesarean delivery can help improve outcomes for many women and make their early postpartum recovery much more pleasant, giving a healthier start for the family.

NCT ID: NCT00375414 Completed - Clinical trials for Head and Neck Neoplasms

Role of Prophylactic Antibiotics in New Introducer PEG-Gastropexy

Start date: October 2003
Phase: N/A
Study type: Interventional

Peristomal infections are the commonest complications of PEG despite prophylactic antibiotics which may result in emergence of resistant micro-organisms like Methicillin resistant Staphylococcus aureus (MRSA). Introducer PEG technique avoids the sojourn of PEG catheter through the oropharynx so chances of infectious complications are negligible. It was not popular because of associated risks and complications. However the new introducer PEG gastropexy has been recently proved to be safe. To determine the incidence of peristomal wound infections during the immediate 7 day post procedure follow up period after the new introducer PEG gastropexy