Weight Cycling Clinical Trial
Official title:
The Effect of Diet Counseling for Low Calorie-High Protein on the Body Composition (Weight, Body Mass Index, Fat Mass (kg), Fat Mass Percentage, Muscle Mass (kg), Muscle Mass Percentage, Inflammation Marker (High-sensitivity C-reactive Protein), and Oxidative Stress Marker (Malondialdehyde and Glutathione) in Obese People With Weight Cycling in Jakarta
The world prevalence of obesity in adult population in 2014 was nearly 13% while in
Indonesia, it has reached 32.9% in the same year. Obesity is an established risk factors for
cardiovascular diseases. A large proportion of people who had succeeded to reduce body weight
failed to maintain it (weight cycling). Studies were inconclusive about the best composition
in the diet for such people to have a better life quality and reduce risk factors from
non-communicable disease. The purpose of this research was to evaluate the body composition
changes, Inflammation marker and oxidative stress marker changes resulted from low calorie
high protein and standard protein diet programme in obese people with history of weight
cycling.
This is an open-randomized clinical trial of weight loss program as a part of a larger study
researching the effect of low calorie high protein diet to body composition, oxidative
stress, inflammation marker and metabolic syndrome in obese with weight cycling. Subjects
were assigned to low calorie diet and were randomly distributed into two intervention groups,
namely high protein group (22-30 % of total calories intake) and standard protein group
(12-20%). Anthropometry, body composition data, and blood sample (for inflammation marker
(HsCRP) and oxidative stress (malondialdehyde and glutathione)) were taken at baseline and at
the end of the study. Subjects were followed up to 8 weeks with daily reminder and weekly
counselling
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT05311462 -
An Observational Cohort Study to Obese Patients With Weight Cycling
|