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Vomiting clinical trials

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NCT ID: NCT01442012 Recruiting - Clinical trials for Postoperative Nausea and Vomiting

Utility of Acupuncture in the Treatment of Postoperative Nausea and Vomiting in Ambulatory Surgery

PUCTURE-NVPO
Start date: September 2011
Phase: N/A
Study type: Interventional

To evaluate the Utility of Acupuncture in the Treatment of Postoperative Nausea and Vomiting (PONV) in Ambulatory Surgery.

NCT ID: NCT01440673 Completed - Clinical trials for Postoperative Nausea and Vomiting

Aprepitant for Postoperative Nausea and Vomiting in Laparoscopic Hysterectomy

Start date: March 2010
Phase: N/A
Study type: Interventional

- Gynecological surgery is associated with a high incidence of postoperative nausea and vomiting. - NK1 receptor antagonists such as aprepitant appear to be highly effective for treating acute and delayed emesis, and yet understanding of the efficacy of different doses of aprepitant is limited. - We performed a prospective, randomized, double-blinded placebo-controlled study of 123 female adults scheduled for laparoscopic hysterectomy who received 80 mg aprepitant, 125 mg aprepitant, or a placebo.

NCT ID: NCT01440465 Completed - Cancer Clinical Trials

Management of Nausea and Vomiting Chemotherapy-induced in Normandy

NAVI
Start date: July 2011
Phase: N/A
Study type: Observational

The objective of this study was to evaluate the various parameters involved in the occurrence of nausea / vomiting during the first cycle of chemotherapy for solid tumors or hematologic among a group of chemotherapy-naive patients, despite anti standardized-emetics protocols.

NCT ID: NCT01434017 Completed - Clinical trials for Postoperative Nausea and Vomiting

Comparison of Three Different Prophylactic Treatments of Postoperative Nausea and Vomiting (PONV) in Children

Start date: November 2008
Phase: Phase 4
Study type: Interventional

Incidence of postoperative nausea and vomiting (PONV) in children after tonsillectomy with or without adenoidectomy may be as high as 75%. Several medications may prevent and treat PONV, such as steroids, antidopaminergic drugs and serotonin (5-HT3) antagonists. The objective of this study is to compare three prophylactic antiemetic treatments: - dexamethasone alone (250 mcg/kg) - dexamethasone (250 mcg/kg) + droperidol (10 mcg/kg) - dexamethasone (250 mcg/kg) + ondansetron (150 mcg/kg).

NCT ID: NCT01417741 Completed - Clinical trials for Postoperative Vomiting and Nausea

Acupuncture and Nausea/Vomiting in Pediatric Patients

Start date: August 2011
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the effects of intraoperative P6 acupuncture plus standard therapy on postoperative nausea and vomiting in pediatric patients undergoing tonsillectomy with or without adenoidectomy. 200 children will be randomly assigned to either the treatment or the control group. 1. Treatment Group: Standard anti-emetic therapy plus bilateral P6 acupuncture after the induction of anesthesia 2. Control Group: Standard anti-emetic therapy only This study will monitor nausea, retching, and vomiting events both directly after the surgery as well as the next day via a follow-up phone call to the parents of the study participant.

NCT ID: NCT01414478 Completed - Emesis Clinical Trials

High Protein Intake to Decrease Emesis and Promote Patient Satisfaction in Labor

Start date: August 2010
Phase: N/A
Study type: Interventional

The purpose of our study is to determine if the incidence of emesis can be lowered with the addition of a high protein drink during labor. Emesis and nausea are the leading causes of parturient dissatisfaction, results in a delay of returning to normal, daily living and can hugely impact the mother's postpartum experience. To date, no studies have been done on the relationship of protein intake during labor and incidence of emesis. To the best of our knowledge, the use of a high protein drink during labor has not been evaluated in the literature.

NCT ID: NCT01405924 Terminated - Nausea Clinical Trials

Fosaprepitant (MK-0517, EMEND® IV) In Salvage Treatment of Chemotherapy-Induced Vomiting (MK-0517-030)

EVADE
Start date: October 25, 2011
Phase: Phase 2
Study type: Interventional

This study will assess the efficacy of a single dose of intravenous (IV) fosaprepitant (MK-0517, EMEND® IV) as salvage therapy when added to a 5-hydroxytryptamine receptor 3 antagonist (5-HT3 RA) and dexamethasone for the prevention of chemotherapy-induced vomiting (CIV) in participants who experienced CIV in the first cycle of moderately emetic chemotherapy (MEC). The primary hypothesis is that there will be no vomiting and no retching in at least 20% of participants during the second cycle of MEC in participants who previously experienced vomiting during the first cycle of MEC.

NCT ID: NCT01395901 Completed - Clinical trials for Postoperative Nausea and Vomiting

Safety and Efficacy of Palonosetron IV to Prevent Postoperative Nausea and Vomiting in Pediatric Patients

Start date: June 2011
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to evaluate the efficacy of a single palonosetron IV dose compared to a single ondansetron IV dose in the prevention of postoperative nausea and vomiting through 24 hours after surgery in children aged from neonates up to less than 17 years undergoing elective surgical procedures requiring general intravenous anesthesia. The secondary objective is to evaluate the safety and tolerability of IV palonosetron in pediatric patients.

NCT ID: NCT01394536 Withdrawn - Clinical trials for Post-operative Nausea and Vomiting

Overnight Use of Electroacustimulation on Postoperative Nausea and Vomiting in the Outpatient Surgery Population

Start date: June 2011
Phase: N/A
Study type: Interventional

Postoperative nausea and vomiting after outpatient surgery are significant sources of patient dissatisfaction. The prevention of postoperative nausea and vomiting (PONV) should be equally as important as prevention of pain because both are large sources of patient dissatisfaction and can necessitate admission after routine outpatient procedures. None of the currently available pharmacological interventions are able to totally abolish PONV. The use of electroacustimulation is a useful adjunct in prevention of PONV, but has yet to be studied when the patient takes the device home with them after leaving an outpatient facility.

NCT ID: NCT01394406 Completed - Clinical trials for Postoperative Nausea and Vomiting

Effect of Ketamine Added to Intravenous Patient-controlled Analgesia on Postoperative Pain, Nausea and Vomiting in Patients Undergoing Lumbar Spinal Surgery

Start date: January 2010
Phase: Phase 4
Study type: Interventional

Ketamine added to intravenous patient-controlled analgesia may be effective on prevention of postoperative nausea and vomiting by reducing opioid requirement after surgery.