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Vomiting clinical trials

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NCT ID: NCT01636947 Completed - Nausea Clinical Trials

A Korean Study of Efficacy and Safety of Aprepitant-based Triple Regimen for the Prevention of Chemotherapy-Induced Nausea and Vomiting in the First Cycle of Moderately Emetogenic Chemotherapy (Non-doxorubicin Hydrochloride [Adriamycin] and Cyclophosphamide Regimens) (MK-0869-225) (KMEC)

KMEC
Start date: December 12, 2012
Phase: Phase 4
Study type: Interventional

This is an efficacy and safety study to compare aprepitant with ondansetron for the prevention of nausea and vomiting in the first cycle of moderately emetogenic chemotherapy (MEC) in participants with solid tumors. MECs include a number of commonly used cancer chemotherapeutic drugs including: oxaliplatin-based, irinotecan-based, and carboplatin-based regimens. The primary hypothesis of this study is that the Aprepitant Regimen is superior to the Control (ondansetron) Regimen with respect to the percentage of participants with No Vomiting Overall (in the 120 hours following initiation of MEC) in participants with solid tumors.

NCT ID: NCT01629992 Completed - Postoperative Pain Clinical Trials

Preoperative Counseling in Cholecystectomy

Start date: January 2009
Phase: Phase 2/Phase 3
Study type: Interventional

The investigators examined whether a written plus verbal preoperative counseling for patients undergoing open cholecystectomy would improve perioperative symptoms such as nausea, vomiting and pain.

NCT ID: NCT01617837 Completed - Clinical trials for Postoperative Nausea and Vomiting

The Efficacy of P6 Acupressure in Reducing Postoperative Nausea and Vomiting in Patients Undergoing Craniotomy

Start date: November 2011
Phase: Phase 2/Phase 3
Study type: Interventional

The aim of this study is to investigate if P6 acupressure may reduce postoperative nausea and vomiting in neurosurgical patients undergoing craniotomy.

NCT ID: NCT01602692 Completed - Pain, Postoperative Clinical Trials

A Comparison of Tumescence in Breast Reduction Surgery

Start date: August 2012
Phase: Phase 4
Study type: Interventional

The investigators' main hypothesis is that in breast reduction surgery, the use of tumescent solution containing both dilute lidocaine and epinephrine will lead to better control of postoperative pain, nausea, vomiting, shorter time through postoperative phases of care, quicker discharge from the hospital and lower numbers of hospital readmissions than the use of tumescent solution containing only dilute epinephrine.

NCT ID: NCT01596426 Withdrawn - Clinical trials for Chemotherapy Induced Nausea and Vomiting

Safety and Pharmacokinetics of Sancuso and IV Granisetron in Patients Aged 2 to 5 Years

Start date: n/a
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine the dosing strategy for adolescents aged 2 to 5 years.

NCT ID: NCT01596413 Withdrawn - Clinical trials for Chemotherapy Induced Nausea and Vomiting

Pharmacokinetics and Safety of Sancuso and IV Granisetron in Pediatrics Aged 6 to 12 Years

Start date: n/a
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine the dosing strategy for adolescents aged 6 to 12 years.

NCT ID: NCT01596400 Completed - Clinical trials for Chemotherapy Induced Nausea and Vomiting

Safety and Pharmacokinetics of Sancuso and IV Granisetron in Patients Aged 13 to 17 Years

Start date: May 2012
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine the dosing strategy for adolescents aged 13 to 17 years.

NCT ID: NCT01594749 Completed - Clinical trials for Chemotherapy-Induced Nausea and Vomiting (CINV)

Efficacy and Safety of Fosaprepitant Dimeglumine in Preventing Chemotherapy-Induced Nausea and Vomiting (MK-0517-031)

Start date: September 24, 2012
Phase: Phase 3
Study type: Interventional

This study aims to demonstrate that, when given concomitantly with a 5-hydroxytryptamine 3 (5-HT3) antagonist and a corticosteroid, a single 150 mg intravenous (IV) dose of fosaprepitant given on Day 1 is superior to the control regimen of 5-HT3 antagonist and corticosteroid only, in preventing chemotherapy-induced nausea and vomiting (CINV) associated with moderately emetogenic chemotherapy (MEC).

NCT ID: NCT01592708 Completed - Clinical trials for Post-operative Nausea

Study of Anesthesia Techniques to Reduce Nausea and Vomiting After Jaw Corrective Surgery

Start date: June 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether a multi-modal anesthesia and pain control protocol reduces post-operative and post-discharge nausea and vomiting (PONV and PDNV) in patients undergoing upper jaw corrective surgery.

NCT ID: NCT01590147 Completed - Pain Clinical Trials

Supportive Intervention Programs Study

SIPS
Start date: June 2011
Phase: N/A
Study type: Interventional

This randomized clinical trial studies the preliminary efficacy of a yoga skills training (YST) compared to counseling and education (CE) for reducing treatment-related symptoms in patients with colorectal cancer who are receiving chemotherapy. The YST may reduce fatigue, other treatment-related symptoms, and improve the quality of life (QOL) of patients with colorectal cancer. It is not yet known whether YST is more effective then CE in reducing these outcomes.