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Vomiting clinical trials

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NCT ID: NCT03870685 Active, not recruiting - Postoperative Pain Clinical Trials

Surgical Site Infiltration of Exparel vs TAP Block With Exparel in Patients Undergoing Laparotomy Via Midline Incision

Start date: July 5, 2018
Phase: Phase 4
Study type: Interventional

This is a randomized-controlled prospective study to be conducted at Danbury Hospital and Norwalk Hospital to compare postoperative opioid consumption and pain scores of patients with suspected or known gynecologic malignancies undergoing midline laparotomy who received TAP block with liposomal bupivacaine versus surgical site infiltration of liposomal bupivacaine. Primary outcome: Total postoperative opioid consumption as measured by morphine equivalents over 48 hour period. Secondary outcomes include: Pain scores (based on visual analog scale 1-10) at 2 hours, 6 hours, 12 hours, 24 hours and 48 hours postoperatively at rest and upon exertion (Valsalva maneuver), Severity of nausea, Episodes of vomiting, Total antiemetics consumption over 48 hour period.

NCT ID: NCT03712891 Active, not recruiting - Clinical trials for Patient Satisfaction

Evaluation of Providing Coffee to Patients Postoperatively to Decrease Length of Stay in the PACU

Start date: October 25, 2018
Phase: N/A
Study type: Interventional

The purpose of the study is to determine if providing coffee to patients who self-identify as coffee drinkers postoperatively will decrease the length of stay in the post-anesthesia care unit (PACU).

NCT ID: NCT03645239 Active, not recruiting - Pain, Postoperative Clinical Trials

Post-operative Emesis and Pain Outcomes After Cesarean Delivery

EPOC
Start date: May 24, 2018
Phase:
Study type: Observational

Approximately 20% women who undergo cesarean delivery would suffer from severe post-operative pain, which may further increase their risks from developing postpartum depression. Predictive factors such as pre-operative pain, age and anxiety could significantly contribute to post-operative nausea and vomiting (PONV) and pain in general surgery, however little information is available with regards to cesarean delivery. The investigators would investigate the risk factors of causing post-operative emesis after cesarean delivery, and to reaffirm that there is a positive correlation between pain on local anesthetic injection, presence of mechanical temporal summation (MTS) and post-Cesarean pain scores.

NCT ID: NCT03405324 Active, not recruiting - Clinical trials for Chemotherapy-induced Nausea and Vomiting

Effect of tDCS of the Motor Cortex on Chemotherapy Induced Nausia and Vomiting

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

this work is looking for the effect of tDCS of the motor cortex on the chemotherapy induced nausea and vomiting in cancer breast patients

NCT ID: NCT03112278 Active, not recruiting - Tooth Erosion Clinical Trials

Clinical Evaluation of Ultrathin Occlusal Veneers for the Treatment of Severe Dental Erosion

UOVTDE
Start date: November 2015
Phase: N/A
Study type: Interventional

Ultra-thin bonded posterior occlusal veneers represent a conservative alternative to traditional onlays and complete coverage crowns for the treatment of severe erosive lesions. Therefore, the purpose of this study is to determine whether ceramic and composite resin ultrathin occlusal veneers (0.6 - 1.0 mm thick) are effective in the rehabilitation of patients affected by moderate and severe dental erosion.

NCT ID: NCT02576327 Active, not recruiting - Vomiting Clinical Trials

A Study Evaluating the Efficacy and Safety of Aprepitant in Autologous Hematopoietic Stem Cell Transplantation

Start date: October 2015
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of additional aprepitant to standard antiemetic regimen in Autologous Hematopoietic Stem Cell Transplantation.

NCT ID: NCT02510183 Active, not recruiting - Clinical trials for Postoperative Complications

P6 Acupressure Before Laparoscopic Cholecystectomy

Start date: February 2015
Phase: N/A
Study type: Interventional

This study is to evaluate the effect of preoperative acupressure application on Postoperative nausea and vomiting (PONV) in patients undergoing laparoscopic cholecystectomy in terms of being in high risk group for PONV.

NCT ID: NCT02473042 Active, not recruiting - Breast Cancer Clinical Trials

Intraoperative Acupoint Stimulation to Prevent Post-Operative Nausea and Vomiting (PONV)

Start date: February 29, 2016
Phase: N/A
Study type: Interventional

The goal of this clinical research study is to learn if light electrical stimulation to the wrist area during surgery is feasible in women having breast surgery.

NCT ID: NCT02016807 Active, not recruiting - Diarrhea Clinical Trials

ZeroTolerance Mucositis: Managing Oral and Alimentary Mucositis With High Potency Sucralfate - ProThelial

Start date: January 2013
Phase: Phase 4
Study type: Observational

RATIONALE: Polymerized (cross-linked) sucralfate malate paste (ProThelial) may be an effective single therapy approach for the management of chemoradiation mucositis, treating and preventing its occurrence in the oral cavity, esophagus, stomach, small and large intestine. PURPOSE: This observational multi-phase trial is studying how well polymerized (cross-linked) sucralfate malate paste (ProThelial) works to prevent and treat mucositis in adult patients who are to receive or have received chemo/radiation therapy that have caused or is anticipated to cause mucositis in the oral cavity, esophagus, stomach, small or large intestine. The Phase IV study addresses prevention and treatment in the oral cavity. The Phase I study addresses prevention and treatment in the esophagus, stomach, small and large intestine.

NCT ID: NCT01913990 Active, not recruiting - Emesis Clinical Trials

Prevention of Chemotherapy Induced Nausea and Vomiting in Breast Cancer Patients.

ER11-02
Start date: September 2011
Phase: Phase 4
Study type: Interventional

For breast cancer patients receiving chemotherapy regimens, the use of a validated emesis (nausea and vomiting) risk calculator will provide superior anti-emetic (nausea and vomiting) control compared with "standard" anti-emetic regimen. The risk calculator has the potential to provide more individualized anti-emetic regimen by decreasing the use of toxic/costly anti-emetics in patients at low risk and possibly more importantly enhancing the appropriate anti-emetic regimen in patients at high risk.