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Vomiting, Postoperative clinical trials

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NCT ID: NCT04618146 Recruiting - Pain, Postoperative Clinical Trials

Enhanced Recovery After Cesarean Section With Low Dose Intrathecal Morphine.

Start date: November 10, 2020
Phase: N/A
Study type: Interventional

This study is designed to see the effect of low dose intrathecal morphine on promting enhanced recovery after cesarean delivery with early ambulation and reduction of hospital stay.

NCT ID: NCT04613726 Completed - Clinical trials for Postoperative Complications

The Effect of Intravenous Granisetron and Ondansetron in Patients Undergoing Cesarean Section

Start date: December 3, 2018
Phase: Phase 3
Study type: Interventional

This study compared the effects of prophylactic intravenous (IV) infusion of ondansetron and granisetron before the spinal anesthesia on hemodynamic parameters in patients undergoing elective cesarean section.

NCT ID: NCT04589429 Recruiting - Pain, Postoperative Clinical Trials

Adding Nalbuphine for Control of Intrathecal Morphine Pruritus

Start date: October 15, 2020
Phase: Phase 2
Study type: Interventional

Intrathecal morphine causes intense itching which is very bothersome. Nalbuphine antagonizes this effect when given intravenously. This trial is to find out if nalbuphine added to intrathecal morphine has an effect on morphine related pruritus while still maintaining adequate analgesia.

NCT ID: NCT04533867 Completed - Pain, Postoperative Clinical Trials

Palonosetron vs. Ondansetron for Postoperative Nausea and Vomiting in Bariatric Surgery

Start date: August 15, 2020
Phase:
Study type: Observational [Patient Registry]

Evaluate the safety and efficacy of palonosetron versus ondansetron to reduce and control post-operative nausea in bariatric surgery.

NCT ID: NCT04442568 Not yet recruiting - Pain, Postoperative Clinical Trials

Impact of ERAS in LSG

ERAS-LSG
Start date: July 1, 2020
Phase: N/A
Study type: Interventional

Patients with BMI >35 and chronic diseases or BMI >40 will be scheduled to receive Laparoscopic Sleeve Gastrectomy (LSG). Two groups are planned according to receive Enhance recovery after surgery (ERAS) protocol or not. All participants will receive standard LSG. Participants of ERAS will receive anesthesia and post-surgical nutrition protocol which are determined for ERAS. All patients will be checked for status of pain with VAS score, nausea and vomiting with PONV score at postoperative 2nd hour, 12th hour. In ERAS group liquid oral intake will be started between postoperative 2nd and 4th hours. In no ERAS group liquid oral intake will be started in the morning of postoperative first day. The patients who provides discharge criterias will be discahrged. these criterias are; To provide adequate pain relief with paracetamol and nonsteroidal painkillers, No wound problem, No complications after surgery, Pulse rate <90 beats / min, temperature ≤ 37 · 5 ° C, respiratory rate, <20 breaths / minute, To be able to mobilize easily, To be able to drink 1 liter of water after surgery. Emergency admissions of the participants within a month after surgery will be recorded.

NCT ID: NCT03645239 Active, not recruiting - Pain, Postoperative Clinical Trials

Post-operative Emesis and Pain Outcomes After Cesarean Delivery

EPOC
Start date: May 24, 2018
Phase:
Study type: Observational

Approximately 20% women who undergo cesarean delivery would suffer from severe post-operative pain, which may further increase their risks from developing postpartum depression. Predictive factors such as pre-operative pain, age and anxiety could significantly contribute to post-operative nausea and vomiting (PONV) and pain in general surgery, however little information is available with regards to cesarean delivery. The investigators would investigate the risk factors of causing post-operative emesis after cesarean delivery, and to reaffirm that there is a positive correlation between pain on local anesthetic injection, presence of mechanical temporal summation (MTS) and post-Cesarean pain scores.

NCT ID: NCT03187080 Suspended - Opioid Use Clinical Trials

Enhanced Recovery Strategies in Elective Breast Surgery

Start date: April 2024
Phase: Phase 4
Study type: Interventional

Postoperative pain, nausea, and vomiting are frustrating sequelae of elective breast surgery. Poorly managed postoperative pain can lead to increased opioid use, increased postoperative nausea and vomiting (PONV), delayed return to work and usual activities, unplanned hospital admissions, surgical complications, and patient dissatisfaction. In light of the growing opioid epidemic in the United States, any intervention that potentially minimizes opioid use may have meaningful individual and societal impact. In patients undergoing breast reduction and breast augmentation surgery, multiple techniques for managing postoperative pain are used commonly. One such technique is the use of a paravertebral block (PVB), which is a method of injecting local anesthesia into the area surrounding the spinal nerves in order to decrease sensation and pain in the chests and breasts in the setting of breast surgery. PVB is generally used concomitantly with standard multimodal perioperative pain management including cool compress, non-steroidal anti-inflammatories (NSAIDs), acetaminophen, and opioids. All of these pain management strategies are used at the University of Wisconsin and are considered standard of care for breast surgery nationwide. The overall purpose of this study is to evaluate interventions that aim to optimize pain control, minimize the risk of PONV, and improve recovery after elective breast surgery. We will do this by (1) Comparing PVB with standard pain management strategies in patients undergoing planned breast reduction and breast augmentation, and (2) Comparing "enhanced recovery after surgery" (ERAS) strategies to standard of care for patients undergoing planned breast reduction and breast augmentation. This will be studied using pain assessments, validated surveys, medication logs, and review of medical records.

NCT ID: NCT03104023 Recruiting - Clinical trials for Vomiting, Postoperative

Staple Line Inversion vs Buttressing on Postoperative Vomits After LSG

Start date: January 2017
Phase: Phase 3
Study type: Interventional

Patients undergoing laparoscopic sleeve gastrectomy will be randomized into 2 groups. In one group, a staple line inversion with a running suture of Polypropylene will be performed. In the second group, the gastric section will be performed with a stapler with preloaded buttress material Postoperative nausea and vomits during the first 24 hours will be investigated.

NCT ID: NCT01297010 Completed - Clinical trials for Vomiting Postoperative

Dexamethasone Compared to Ondansetron and Dexamethasone for Prophylaxis of Postoperative Vomiting in Children

vomiting
Start date: March 2011
Phase: Phase 3
Study type: Interventional

The majority of pediatric surgery takes place in an outpatient basis. The occurrence of postoperative vomiting can lead to a delay in hospital discharge. However, the use of postoperative vomiting prophylaxis exposes patients unnecessarily to the drugs side effects and also raises the final costs of the surgical procedure. The Objective our study is Compare the incidence of postoperative vomiting between children who received dexamethasone, dexamethasone plus ondansetron or placebo for anti-emetic prophylaxis during outpatient surgery. This is a randomized, double blind, placebo-controlled study to comparing the use of dexamethasone, dexamethasone plus ondansetron and placebo for postoperative vomiting prophylaxis in children submitted to general anesthesia. Data analysis will be used is Fisher's exact test for the categorical variables and the Anova test for numerical variables as they presented Gaussian variation. The study used a significance level of 5%.