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Vision Disorders clinical trials

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NCT ID: NCT06000865 Recruiting - Glaucoma Clinical Trials

Glaucoma Rehabilitation With Action viDeo Games and Exercise - GRADE

Start date: September 9, 2023
Phase: N/A
Study type: Interventional

Falls are one of the most serious public health concerns for seniors, with significant medical and economic consequences. This concern is even higher in patients with peripheral field loss due to glaucoma because of the patients' compromised visual input. The investigators' project proposes an innovative, entertaining, easily accessible and enjoyable intervention for improving mobility and postural control function in glaucoma patients with peripheral vision loss, who are more prone to falls and suffer from fear of falling. The new intervention examined in this project can be implemented in current vision and balance rehabilitation programs, and may benefit patients with different types of visual impairment to minimize their risk of falls and improve their quality of life.

NCT ID: NCT05976880 Completed - Visual Impairment Clinical Trials

Grip Effects of Power Ball in Children

Start date: July 15, 2023
Phase: N/A
Study type: Interventional

A broad definition of visual impairment includes a wide continuum of visual function loss. Aspects of visual function include visual acuity, which is the capacity to resolve detail, and accommodation (capacity to concentrate), field of vision (the area that may be seen), colour perception, and light sensitivity. A child with cerebral blindness can nevertheless be able to perceive motion. There are numerous sources of prevalence information, each of which has drawbacks. One of the fundamental pillars of the major worldwide prevention of blindness project, VISION 2020 the Right to Sight, is the reduction of visual impairment and blindness in children in resource-poor nations. Refraction and poor vision services aid visually impaired children, especially those with genetic or congenital ocular defects and enable vision improvement.

NCT ID: NCT05967078 Recruiting - Clinical trials for Cognitive Impairment

ExerG: Video Game-based Physical Cognitive Training for Patients: a Usability Study

ExerGetic
Start date: May 16, 2023
Phase: N/A
Study type: Interventional

Video game-based training programs, in the following referred to as "exergames" are an innovative digital training approach to simultaneously train physical and cognitive functions and increase training motivation for various populations. Patients who are differently limited in their physical and cognitive performance due to a decline in functioning can profit from a motivating and combined physical-cognitive training approach. An interdisciplinary team of movement scientists, sports and training experts, as well as game and industrial designers developed an innovative and immersive video game-based training product for patients - the ExerCube training software licence. The exergame development focused on a user-centred process together with the target population. The ExerCube training software licence is an exergame training product that includes immersive mixed-reality training programs (or video games) for patients. Depending on the patient's training requirements, the therapists can choose from the training program repertoire. The patients control the training program (or video game) by specific (whole) body movements. To present the virtual training programs from the ExerCube training software licence in the physical environment, the ExerCube hardware and harness system is used to serve as a physical training room. It allows the virtual video game environment to be presented in the physical world. This summative usability study aims to assess the training system's safety, usability and validate the user experience. Primary end-users (defined as patients aged 18 and above) and secondary end-users (defined as sports scientists, training therapists or physiotherapists/occupational therapists with a focus on sports/training therapy) will test and review the system in different testing scenarios.

NCT ID: NCT05921240 Not yet recruiting - Vision Disorders Clinical Trials

Unmet Needs, Barriers and Facilitators to Vision Services for Children and Adolescents With Special Vision Care Needs: A Mixed-Model Design Study

SN(vision)
Start date: June 20, 2023
Phase:
Study type: Observational

Children and adolescents with special needs, compared to those with general development, have a much higher incidence of visual impairments (10.5% vs. 0.16%). This project will focus on "children and adolescents with special visual care needs", comprehensively exploring their unmet needs in ophthalmology and visual care, as well as the obstacles and facilitators they may encounter in the process of seeking ophthalmic services. The purposes of this study will investigate the current needs of children and adolescents with special visual care needs in ophthalmology and visual medical services, and the obstacles and potential facilitators encountered by children and adolescents with special visual care needs in the process of obtaining ophthalmology and visual medical services.

NCT ID: NCT05901350 Completed - Parkinson Disease Clinical Trials

The Correlation of Reduction of Levodopa and Non-motor Symptoms of Parkinson's Disease After Deep Brain Stimulation

Start date: June 1, 2019
Phase: N/A
Study type: Interventional

Patients with parkinson disease (PD) usually reduced the dose the levodopa after received deep brain stimulation (DBS). However, studies seldomly mentioned about the influences on non-motors systems after the reduction. Our study focused on the changes after DBS and attribute them to the levodopa variety.

NCT ID: NCT05865093 Recruiting - Visual Impairment Clinical Trials

Early Visual Functions in Patients at Risk of Developing Cerebral Visual Impairment. A Pilot Study

Start date: July 1, 2022
Phase:
Study type: Observational

The aim of the study is to assess visual function from neonatal age to 36 months of age in infants at risk of visual impairment due to brain lesion or ocular pathology

NCT ID: NCT05844982 Recruiting - Visual Impairment Clinical Trials

Intravitreal Faricimab Injections or Fluocinolone Acetonide (0.19 mg) Intravitreal Implants vs Observation for Prevention of VA Loss Due to Radiation Retinopathy

AL
Start date: November 21, 2023
Phase: Phase 3
Study type: Interventional

This randomized controlled trial will evaluate the effect of intravitreal faricimab or fluocinolone acetonide (FAc) intravitreal implant compared with observation on long-term visual acuity following treatment of choroidal melanoma with iodine-125 plaque brachytherapy.

NCT ID: NCT05835193 Completed - Refractive Errors Clinical Trials

Pre-symptomatic Screening of Visual Acuity in Pre-school Students

Start date: April 20, 2023
Phase:
Study type: Observational

The present research process is a prospective, non-interventional clinical study that will be conducted -under the auspices of the Democritus University of Thrace (DUTH)- in the pre-school students of the city of Alexandroupolis, Greece. - The study aims to assess the visual acuity of the kindergarten students. - The measurement of monocular best-spectacle corrected visual acuity will be performed using a web-based visual acuity chart

NCT ID: NCT05829135 Recruiting - Visual Impairment Clinical Trials

Improving Glare and Visual Comfort for Patients With Visual Impairment

Start date: May 1, 2023
Phase: N/A
Study type: Interventional

To assess the use of contact lenses with transitions technology to improve glare, light sensitivity and overall visual comfort in patients with visual impairment.

NCT ID: NCT05809973 Recruiting - Stroke, Acute Clinical Trials

The Oslo Study of Visual Impairment After Stroke (StrokeVIS)

StrokeVIS
Start date: November 15, 2021
Phase:
Study type: Observational

Longitudinal, prospective, single-center observational study of visual impairment after stroke. Population: Patients admitted with acute ischemic stroke at the Regional Stroke Unit at Oslo University Hospital who are assessed to not have more serious neurological deficits than to be eligible for a prospective observational study of visual impairment. National Institute of Health Stroke Scale (NIHSS) will be used for screening of the patients eligible for the study with cut off of NIHSS 20. Based on the number of patients admitted to our center to include 120 patients in the StrokeVIS study. The study aims are: 1. To determine the prevalence of visual impairment in stroke patients in the acute phase and after 3 months. 2. To compare visual impairment in those treated with EVT and those not. 3. To determine the sensitivity and specificity of the Vision Screening Assessment (VISA) tool for detection of visual impairment in stroke patients. 4. To assess possible association between brain MRI lesions and visual impairment in stroke patients in the acute phase. 6) To assess any cognitive deficits at 3-month follow-up that could impact visual function. Inclusion criteria: 1. Acute ischemic stroke and NIHSS < 20 2. Age ≥18 years. 3. Written informed consent of the patient or oral informed consent witnessed by a doctor. Exclusion criteria: 1. NIHSS < 20 2. No willingness and ability of the patient to participate in all baseline and follow-up examinations. Duration of study participation: 3 months.