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Ventricular Premature Complexes clinical trials

View clinical trials related to Ventricular Premature Complexes.

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NCT ID: NCT06203262 Recruiting - Clinical trials for Ventricular Tachycardia

Ventricular Catheter Ablation Study (VCAS)

VCAS
Start date: April 12, 2024
Phase: N/A
Study type: Interventional

This is a prospective safety and feasibility study to evaluate the safety of the FieldForceâ„¢ Ablation system in patients with ventricular arrhythmia divided into two groups: VT (VCAS-I) and frequent premature ventricular complex (VCAS-II).

NCT ID: NCT06060548 Recruiting - Myocarditis Clinical Trials

Role of Novel ILR in the Management of PVCs

Start date: April 20, 2022
Phase:
Study type: Observational

This prospective, observational study is a single center clinical registry of patients referred for management of symptomatic or asymptomatic Premature Ventricular Contractions (PVCs). Subjects will be followed through 12 months. The study will enroll approximately 50 patients.

NCT ID: NCT06021613 Recruiting - Clinical trials for Premature Ventricular Contractions

The MARY-JANE Cannabis and Heart Rhythm Trial

Start date: January 18, 2023
Phase: N/A
Study type: Interventional

Despite recreational cannabis now being legal in 23 states, where more than 100 million Americans reside, studies on the actual health effects are limited. This study is a randomized trial, where each participant will be instructed to consume or avoid cannabis on randomly assigned days during a 14-day monitoring period. The goal of this study is to answer the question: "Does cannabis use increase the frequency of 'early' and abnormal heart beats?" During the 14-day period, participants will wear an external heart monitor, a glucose monitor, and a fitness tracker to track heart rhythm, glucose levels, step counts, and sleep health. Participants will use a mobile app or a text messaging service for daily instructions/reminders on cannabis use, and short surveys. The investigators ask that participants smoke or vape cannabis at least once on days they are instructed to consume cannabis. Compelling evidence of heart and other health effects would be important to the clinical care of our patients.

NCT ID: NCT05866731 Recruiting - Clinical trials for Premature Ventricular Contraction

The Heart Rhythm Twins Study

Start date: March 22, 2022
Phase:
Study type: Observational

Premature atrial contractions (PACs) and premature ventricular contractions (PVCs) are observed in the majority of individuals monitored for more than a few hours. Although the clinical course of PACs and PVCs is usually benign, it has been described that high PAC or PVC frequency causes various comorbidities and worsens outcomes in different patient groups. For example, PACs can initiate episodes of atrial fibrillation, and PAC count is highly specific in predicting diagnosis of incident atrial fibrillation. Increasing PVC frequencies are an important predictor of incident heart failure. While conventional wisdom dictates that common environmental exposures determine PAC and PVC frequencies, this has not born out in rigorous studies. Whether PAC and PVC frequencies may have genetic underpinnings remains unknown. Comparisons between identical twins and fraternal twins can provide estimates of heritability. Fraternal twins are an ideal control because, like identical twins, they share a womb, have the same birthday, and their environment while growing up are as similar as between identical twins. However, while identical twins share approximately 100% of the same inherited DNA, fraternal twins share, on average, about 50%. By monitoring identical and fraternal twins with portable electrocardiograms (ECGs), we will be able to count the PACs and PVCs over a consecutive timespan to describe the familial aggregation of these complexes. This, to our knowledge, would be the first study to compare PAC and PVC frequencies in identical and same-sex fraternal twins, providing the first assessment of how genetical inheritance may influence cardiac ectopy burdens.

NCT ID: NCT05341544 Recruiting - Clinical trials for Premature Ventricular Contraction

Non-invasive Vagal Stimulation for Frequent Premature Ventricular Complexes

(NoVa-PVC)
Start date: August 22, 2022
Phase: N/A
Study type: Interventional

A prospective sham-controlled randomized clinical trial to assess the effect of low-level tragus stimulation (LLTS) in patients with frequent premature ventricular complexes (PVCs)

NCT ID: NCT05061498 Recruiting - Catheter Ablation Clinical Trials

Impact of Pacing Output and Cycle Length on QRS Morphology

Start date: December 1, 2021
Phase: N/A
Study type: Interventional

Current recommendations for pacemapping are based on expert opinion and animals models. Present study sought to evaluate the influence of different parameters of pacemapping on QRS morphology. Pacemapping is performed with different cycle length (fixed burst vs. coupling interval) and stimulation output (maximum output vs. threshold) and resulting QRS complexes are compared to clinical PVC and the standard of care to determine the optimal parameter setting in pacemapping.

NCT ID: NCT04909528 Recruiting - Clinical trials for Premature Ventricular Contraction

LLTS to Treat Premature Ventricular Contractions

TREAT-PVC
Start date: March 15, 2021
Phase: N/A
Study type: Interventional

This randomized control trial is designed to explore the effect of low-level tragus stimulation in patients with frequent premature ventricular contractions.

NCT ID: NCT04778696 Recruiting - Heart Failure Clinical Trials

PASO Automated Template Matching for PVC Ablation

PAsT-PVC
Start date: February 5, 2018
Phase: N/A
Study type: Interventional

Pacemapping is an essential tool during ablation of idiopathic PVC and VT. Automated template matching has been shown to have a significant influence on PVC ablation procedures, but the PASO module of CARTO3 has not been studied in a randomized trial. The Aim of this study is to evaluate the additional benefit of PASO template matching on PVC ablation procedure with regard to procedural parameters and outcome when compared with conventional pace mapping. A total of 144 pts will be randomised in a 1:1 fashion to PVC ablation guided by conventional pacemapping vs PVC ablation guided by PASO pacemapping. Patients will be follow up with Holter-ECG and TTE after 3 and 12 months.

NCT ID: NCT04637230 Recruiting - Atrial Fibrillation Clinical Trials

Prevention of Stroke and Sudden Cardiac Death by Recording of 1-Channel Electrocardiograms

PRICE
Start date: October 1, 2021
Phase:
Study type: Observational [Patient Registry]

Single-channel electrocardiograms (lead I of 12-lead surface ECG; 30 seconds) will be collected from subjects/patients at 11 clinical centers in Germany to train an Artificial Intelligence in the automatic diagnosis of regular and irregular heart rhythms. Heart rhythms of interest are normal sinus rhythm (SR), atrial fibrillation (AF), atrial premature beats (APBs), ventricular premature beats (VPBs), and nonsustained ventricular tachycardia (VT). Per diagnosis, 20,000 ECGs are required, for a total of 100,000 ECGs to be obtained from approximately 10,000 subjects/patients.

NCT ID: NCT04617717 Recruiting - Clinical trials for Ventricular Premature Complexes

Personalized Treatment for Patients With Premature Ventricular Beats

Start date: September 30, 2020
Phase:
Study type: Observational

Frequent premature ventricular beats (PVBs) are common, negatively affects the quality of life for many patients, and can lead to impaired contractile function. Rule-out of structural heart disease is key in the assessment of PVBs. Cardiac MR has a high sensitivity for structural heart disease, but the diagnostic gain from this resource-demanding procedure in the work-up of patients with PVBs is unknown. There is a need to establish the role of MR in the evaluation of patients with PVBs to improve diagnostic efficacy, establish treatment strategies, and promote further research. This project will answer three key questions: 1) What is the diagnostic gain from cardiac MR in patients with PVBs? 2) Is MR the real gold standard to rule-out structural heart disease in patients with PVBs? 3) Can non-invasive heart rate parameters guide the strategy for induction of PVBs during invasive electrophysiological procedures?