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Ventricular Fibrillation clinical trials

View clinical trials related to Ventricular Fibrillation.

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NCT ID: NCT02982473 Recruiting - Clinical trials for Ventricular Tachycardia

Registry of Malignant Arrhythmias and Sudden Cardiac Death - Influence of Diagnostics and Interventions

RACE-IT
Start date: April 2016
Phase:
Study type: Observational

The "Registry of Malignant Arrhythmias and Sudden Cardiac Death - Influence of Diagnostics and Interventions (RACE-IT)" represents a mono-centric registry of patients being hospitalized suffering from malignant arrythmias (ventricular tachycardia or fibrillation) and sudden cardiac death (SCD). Detailed findings of patients' clinical outcome regarding mortality and co-morbidities related to the presence of invasive diagnostics or therapies including coronary angiography, percutaneous coronary intervention (PCI), electrophysiological testing (EP), catheter ablation and implanted cardiac devices (e.g. implantable cardioverter-defibrillators) will be documented. Patients will be included when being hospitalized from the year 2004 until today.

NCT ID: NCT02882139 Recruiting - Clinical trials for Arrhythmias, Cardiac

International Electrical Storm Registry

ELECTRA
Start date: August 2016
Phase:
Study type: Observational [Patient Registry]

Organized ventricular arrhythmias (ventricular tachycardia (VT), torsades de pointes (TdP) and ventricular fibrillation (VF)) represent a major event in the clinical history of a patient and they can lead to hemodynamic instability and sudden cardiac death (SCD). Recurrences of ventricular arrhythmias and electrical instability have exponentially increased in the last decades and a new clinical entity called "electrical storm" (ES) has emerged as major morbidity and mortality factor. The ES is defined as a cluster of 3 or more sustained ventricular arrhythmias within 24 hours, or a sustained ventricular tachycardia lasting 12 hours or more and that does not respond to treatments. Most of the patients presenting ES are already implanted with an ICD. This is due to 3 factors: first, patients with ICD implant are at higher risk to develop ventricular arrhythmias for the cardiac disease that led to the ICD implant. Second, the device records and treats also asymptomatic or poor symptomatic arrhythmic episodes that otherwise would not be detected. Third, and more important, the device gives the possibility to survive to an arrhythmic episode, making it possible for the patient to experience an ES. The incidence of ES is debated in different studies and ranges from 10 to 60% in patients with ICD for secondary prevention and from 4 to 7% in patients with ICD for primary prevention. The aim of the ELECTRA registry is twofold: 1. To create an international registry on clinical features, optimal therapy, ablation strategy, prognosis and the effect of ICD programming on patients with ES. 2. To use the data derived from the registry for a prospective, observational study on mortality and rehospitalization rate in patients with ES.

NCT ID: NCT02816047 Recruiting - Heart Failure Clinical Trials

Austrian Wearable Cardioverter Defibrillator Registry

Start date: November 2014
Phase:
Study type: Observational

Background: The wearable cardioverter defibrillator (WCD) is an established treatment option for patients at high risk for ventricular tachycardia / ventricular fibrillation (VT/VF), either in whom this risk may only be temporarily present, or in patients at high risk for sudden cardiac death (SCD) or after VT/VF in whom an implantable cardioverter defibrillator (ICD is currently not possible for other reasons (infection, recent MI <40days, recent PCI/CABG < 3months etc.). Methods: Comprehensive registry including all patients in Austria who received a WCD in 2010-2016.

NCT ID: NCT02513030 Recruiting - Clinical trials for Defibrillation Capacity of Defibrilators After Replacement

Cardioverter Defibrillator Replacement With Induction of Ventricular Fibrillation and Defibrillation Testing

SIMPLER
Start date: August 2015
Phase: N/A
Study type: Observational

The SIMPLE study was a large one, and lasted quite a few years due to its design as a randomized controlled trial and the follow up needed to reach an endpoint. The investigators aim to conduct an observational pilot study looking at frequency of positive findings during VF testing . The comparator will be the rate of findings during testing in the Simple trial. If the investigators will find an increased rate of findings (significantly higher than in the Simple trial ) it may set the stage for a randomized controlled trial of replacements , along the line of the Simple trial , or to a recommendation to continue VF testing in all ICD replacements.

NCT ID: NCT01822145 Recruiting - Clinical trials for Ventricular Tachycardia

A Feasibility Study on Prediction of an ICD Shock by ICD-derived Data

PREDICT-ICDS
Start date: March 2013
Phase: N/A
Study type: Observational

The primary hypothesis is that an ICD shock may be predicted days in advance by a combined score derived from different data obtainable from the ICD

NCT ID: NCT01013714 Recruiting - Clinical trials for Ventricular Tachycardia

Cardiac Sympathetic Denervation for Prevention of Ventricular Tachyarrhythmias

PREVENT VT
Start date: July 26, 2021
Phase: Phase 3
Study type: Interventional

The purpose of this research study is to examine the effect of cardiac sympathetic denervation (CSD) surgery on life threatening abnormal heart rhythms called ventricular tachycardia or ventricular fibrillation that can lead to sudden cardiac death. Subjects will be asked to participate in this research study if they have recurrent ventricular tachycardia (at least one ICD shock for ventricular tachycardia) and have undergone at least one catheter ablation procedure or have ventricular tachycardia or fibrillation that is not ablatable. The goal of this study is to determine whether cardiac sympathetic denervation can prevent these abnormal heart rhythms from occurring and therefore, prevent, ICD shocks which are not only painful, but have been shown to reduce quality of life and/or lead to depression, particularly in the period immediately after the shock.

NCT ID: NCT00196248 Recruiting - Clinical trials for Ventricular Fibrillation

Out-of Hospital Resuscitation Study

Start date: n/a
Phase: Phase 4
Study type: Observational

Sudden cardiac arrest is one of the most common causes of death in industrial countries. The main objective of this study is to built up a register of all out-of hospital resuscitation in a defined area. According to this register, it is possible to evaluate for example predictors of survival to improve training and organisation of prehospital resuscitations.

NCT ID: NCT00176176 Recruiting - Clinical trials for Ventricular Tachycardia

Investigation of Cognitive Function Before and After Induced Ventricular Fibrillation in Electrophysiological (EP) Study

Start date: n/a
Phase: N/A
Study type: Interventional

In this study, changes in electroencephalogram (EEG) and the hemodynamic state during ventricular fibrillation or induced ventricular tachycardia are investigated.

NCT ID: NCT00175942 Recruiting - Clinical trials for Acute Myocardial Infarction

Risk Indicators in Patients With Ventricular Fibrillation During Acute Myocardial Infarction

Start date: February 2003
Phase: N/A
Study type: Observational

Sudden cardiac death is in most cases triggered by ischemia-related ventricular tachyarrhythmias and accounts for 50% of deaths from cardiovascular disease in developed countries. Chronic elevation of indicators of coagulation activation has been found in patients with coronary heart disease , but a role of coagulation activation and proinflammatory state as a potential risk factor for ventricular fibrillation (VF) during acute myocardial infarction has not been investigated.