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Vascular Diseases clinical trials

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NCT ID: NCT00670540 Completed - Pulmonary Embolism Clinical Trials

Epidemiology of Thromboembolism Disease: A Cohort Study

OPTIMEV
Start date: November 2004
Phase: N/A
Study type: Observational

The purpose of this study is to determine different risk factors of thromboembolic disease. Different points will be studied 1. do different types of thromboembolic disease (distal Deep Vein Thrombosis (DVT), proximal DVT, Pulmonary Embolism (PE) and DVT, PE without DVT) have the same clinical significance (risk factors and prognosis) ? 2. Is it necessary to obtain a detailed history of thromboembolic disease ? 3. Do older patients have particular risk factors ? 4. Do preventive treatments modify the level of risk factors and the clinical signs of thromboembolic disease ? 5. Do predictive clinical scores have the same performance for both in and outpatients ? 6. Can patients with a potential high level of thromboembolic risk (surgery, pregnancy) but no clinical thromboembolic symptoms, develop a low risk ? 7. The evolution of the disease in patients with negative or positive Venous ThromboEmbolism (VTE) exploratory tests.

NCT ID: NCT00667381 Completed - Clinical trials for Peripheral Vascular Disease

Femoral Arterial Access With Ultrasound Trial

FAUST
Start date: April 2008
Phase: N/A
Study type: Interventional

This study is designed to evaluate the routine use of vascular ultrasound as an aid for proper placement of a femoral arterial sheath during cardiac catheterization and peripheral arterial angiography.

NCT ID: NCT00662818 Completed - Clinical trials for Cerebrovascular Accident

Telcagepant (MK-0974) Treatment of Migraine in Participants With Stable Vascular Disease (MK-0974-034)

Start date: March 17, 2008
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of telcagepant in the treatment of acute migraine in participants with stable vascular disease. Acetaminophen/paracetamol (APAP) will be used as an active comparator in this study. The primary hypothesis of this study is that telcagepant 300 mg is superior to placebo.

NCT ID: NCT00660764 Completed - Diabetes Clinical Trials

Assessment of the Efficacy of Rosuvastatin in Patient Groups With a Dissimilar Risk Profile in an Observational Study (HEROS)

HEROS
Start date: May 2003
Phase: N/A
Study type: Observational

In an observational multi-centre study (HEROS), the effects of starting treatment with rosuvastatin were assessed, on low-density lipoprotein cholesterol (LDL-C) goal achievement, in patients with a dissimilar high-risk profile who had not been treated with cholesterol lowering drugs at least in the past three months. Also set-up costs of rosuvastatin treatment and proportional changes in LDL-C and high-density lipoprotein cholesterol (HDL-C) were studied.

NCT ID: NCT00652418 Completed - Clinical trials for Peripheral Vascular Diseases

Magnevist (SH L 451A) Intra-individual Dose Comparison Study in Magnetic Resonance Angiography

Start date: July 2004
Phase: Phase 2
Study type: Interventional

The objective of the study was to compare the efficacy of Magnevist (SH L 451 A) at doses of 0.1 mmol/kg and 0.2 mmol/kg in contrast-enhanced 3D-Magnetic Resonance Angiography in three regions (abdominal, femoral, and leg regions) for visualization of arteries, evaluating 179 not assessable: caused by contrast media in the evaluation of structural abnormalities. Magnevist (SH L 451 A) was administered intravenously in a crossover design in patients with arterial disease in the abdominal to leg regions. The safety of the 0.2 mmol/kg dose was also assessed.

NCT ID: NCT00638222 Terminated - Kidney Disease Clinical Trials

Carvedilol and Micro T-Wave Alternans in Hypertensives With Chronic Kidney Disease

Start date: May 2008
Phase: N/A
Study type: Interventional

Evaluate effectiveness of Carvedilol CR on Micro T-Wave Alternans in high risk hypertensives

NCT ID: NCT00637741 Completed - Clinical trials for Critical Limb Ischemia

DURABILITY-200: EverFlex 200mm Long Nitinol Stents in TASC C&D Femoropopliteal Lesions

Start date: March 2008
Phase: Phase 4
Study type: Interventional

The objective of this clinical investigation is to evaluate the long-term (up to 12 months) outcome of the 200 mm long self-expanding nitinol EverFlex (ev3) stent in long femoropopliteal lesions (TASC C & D) Is is the first time that the use of 200 mm long stents will be evaluated in these lesions. It is expected that the outcome of the treatment with this type of long stents will be better as the treatment of identical lesions lengths with multiple shorter stents.

NCT ID: NCT00633659 Completed - Vascular Disease Clinical Trials

Pilot Study of Hemospan® in Patients With Chronic Critical Limb Ischemia

Start date: September 2007
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the effects of Hemospan infusion on vascular reactivity, regional perfusion and oxygenation of ischemic tissue in patients with chronic critical lower limb ischemia.

NCT ID: NCT00616980 Completed - Clinical trials for Peripheral Artery Disease

Injection of Autologous CD34-Positive Cells for Critical Limb Ischemia

ACT34-CLI
Start date: December 2007
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of intramuscular injections of adult stem cells in patients with Critical Limb Ischemia (CLI).

NCT ID: NCT00616668 Completed - Vascular Diseases Clinical Trials

Early Postoperative Fitting of the Air- Limb Prosthesis for Transtibial Amputees

Start date: January 2003
Phase: Phase 2
Study type: Interventional

The aim of the study is to check whether an early adjustment of the Air-Limb prosthesis to Transtibial amputees due to vascular diseases, will shorten the healing time of the stump and the process of rehabilitation.