Varicose Veins Clinical Trial
Official title:
Endovenous Chemical Ablation and Trendlenburg Operation for the Treatment of Great Saphenous Vein Varicosities
Verified date | December 2022 |
Source | Al-Azhar University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Venous insufficiency at lower extremities may result in clinical problems from cosmetic issues to ulcerations. When the frequency of venous insufficiency and its related problems are considered besides their diversity, it is encountered as a public health issue. This pathology is reported to affect 40% of women and 20% of men.1 Patients with varicose veins may complain of unsightly appearance, aching, heaviness, pruritus, and early fatigue of the affected leg. These symptoms worsen with prolonged standing and sitting and are relieved by elevation of the leg above the level of the heart. Also, mild edema is often present. More severe signs include thrombophlebitis, hyperpigmentation, lipodermatosclerosis, ulceration, and bleeding
Status | Completed |
Enrollment | 55 |
Est. completion date | April 5, 2021 |
Est. primary completion date | April 1, 2021 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 20 Years to 60 Years |
Eligibility | Inclusion Criteria: - Patients presented by primary VV of the LL complaining of Leg pain cosmetic disfigurement, leg ulcer, itching, or pigmentation at LL - the incompetence of the saphenofemoral junction (SFJ) and or saphenopopliteal junction (SPJ). Exclusion Criteria: - Lower limb involvement by any of the following conditions; secondary VV, recurrent VV, lymphedema, acute superficial thrombophlebitis, arterio-venous fistula (congenital or acquired), congenital anomalies of the venous system, general comorbidities, skin infection or ischemia |
Country | Name | City | State |
---|---|---|---|
Egypt | Walied Khereba | Zagazig |
Lead Sponsor | Collaborator |
---|---|
Al-Azhar University |
Egypt,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | GSV Patency | Great saphenous Vein Patency: is a categorical outcome that will be assesd by dopler ultrasound. it may be patent or partilly occluded or completely occluded or recanalized. | at one week post operative | |
Primary | GSV Patency | Great saphenous Vein Patency: is a categorical outcome that will be assesd by dopler ultrasound. it may be patent or partilly occluded or completely occluded or recanalized. | at one month post operative | |
Primary | GSV Patency | Great saphenous Vein Patency: is a categorical outcome that will be assesd by dopler ultrasound. it may be patent or partilly occluded or completely occluded or recanalized. | at one year post operative |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT02441881 -
Trial of Radiofrequency Thermo-ablation Treatments of Great Saphenous Varicose Veins (3-RF Study)
|
N/A | |
Completed |
NCT03283800 -
Copper Impact on Venous Insufficiency and Lipodermatosclerosis
|
N/A | |
Recruiting |
NCT02676908 -
Optimum Duration of Compression Stockings After Endovenous Varicose Vein Surgery
|
N/A | |
Withdrawn |
NCT01203397 -
Safety And Efficacy Study Of Topic Mucopolysaccharide Polysulfate In The Superficial Varicose Veins Treatment
|
Phase 3 | |
Withdrawn |
NCT01426035 -
Safety And Efficacy Study Of Topic Mucopolysaccharide Polysulfate Cream In The Superficial Varicose Veins Treatment
|
Phase 3 | |
Recruiting |
NCT02054325 -
Study Protocol Comparing Polidocanol Versus Hypertonic Glucose for Treatment of Reticular Veins
|
Phase 4 | |
Withdrawn |
NCT03601572 -
Hypnoanalgesia in Surgical and Endovenous Treatment of Varicosis
|
||
Completed |
NCT04933591 -
Impact of Treatment With VENARUS® on the Level of Monocyte Chemoattractant Protein 1 in Varicose Veins Blood
|
N/A | |
Active, not recruiting |
NCT02397226 -
Lower Limb Venous Insufficiency and the Effect of Radiofrequency Treatment Versus Open Surgery
|
N/A | |
Withdrawn |
NCT02936271 -
Efficacy of Vasculera in Prevention on Post-op Pain and Edema Following Lower Extremity Venous Treatment in the Outpatient Setting
|
N/A | |
Terminated |
NCT02557542 -
Pilot RCT Evaluating a One Stop Vein Clinic
|
N/A | |
Completed |
NCT00758420 -
Randomized, Single Blind, Placebo Controlled, to Evaluate Efficacy and Safety of Polidocanol Injectable Foam for Treatment of Symptomatic, Visible Varicose Veins With SFJ Incompetence
|
Phase 2/Phase 3 | |
Active, not recruiting |
NCT00841178 -
Endovenous Laser Therapy (EVLT) for Sapheno-Popliteal Incompetence and Short Saphenous Vein (SSV) Reflux: A RCT
|
N/A | |
Not yet recruiting |
NCT05508581 -
Microwaves Ablation of Varicose Veins
|
N/A | |
Completed |
NCT05247333 -
Implementation of a Minor Ailment Service in Community Pharmacy Practice
|
N/A | |
Active, not recruiting |
NCT04339075 -
Registry to Investigate the Efficacy and Safety of VenaBlock VeIn SEaling System for VaRicose Veins in SingApore
|
||
Completed |
NCT03392753 -
Mechanochemical Ablation Compared to Cyanoacrylate Adhesive
|
N/A | |
Recruiting |
NCT04146168 -
Lake Washington Vascular VenaSealâ„¢ Post-Market Evaluation
|
||
Recruiting |
NCT02304146 -
Long-term Ultrasound Guided Foam Sclerotherapy Versus Classical Surgical Stripping Study
|
N/A | |
Completed |
NCT01231373 -
Polidocanol Endovenous Microfoam (PEM) Versus Vehicle for the Treatment of Saphenofemoral Junction (SFJ) Incompetence
|
Phase 3 |