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Valvular Surgery clinical trials

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NCT ID: NCT05211934 Recruiting - Valvular Surgery Clinical Trials

Relationship Between Postoperative Delirium and Heart Function in Valvular Surgery

Start date: January 1, 2022
Phase:
Study type: Observational

Delirium is an acute brain lesion characterized by abnormalities of consciousness, attention, cognition and sensation. Many brain diseases such as stroke, traumatic brain injury and intracranial hypertension can lead to cardiac insufficiency, arrhythmia and heart failure. The incidence of postoperative delirium in patients undergoing cardiac surgery is high. Postoperative delirium is a manifestation of brain function injury. The effect of postoperative delirium on postoperative cardiac function in patients undergoing cardiac surgery is worthy of further discussion.

NCT ID: NCT00890838 Completed - Inflammation Clinical Trials

Preoperative Intravenous Omega 3 Fatty Acids Administration in Valvular Surgery Patients

IVFO-Valvular
Start date: April 2009
Phase: Phase 4
Study type: Interventional

The perioperative administration of n-3 fatty acids has been shown to lead to favorable effects on outcome in patients with severe surgical interventions by lowering the magnitude of inflammatory response and by modulating the immune response. To the investigators' knowledge, no study with preoperative administration of intravenous (IV) omega 3 fatty acids as a part of total parenteral nutrition (TPN) or monotherapy with it to demonstrate its effects on inflammatory and immune response has been conducted. So, this study has been planned to judge the inflammatory response of preoperative monotherapy with IV omega 3 fatty acids in elderly patients undergoing valvular surgery considering the hyperinflammation associated with this type of surgery in elderly patients.