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Urinary Calculi clinical trials

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NCT ID: NCT02983409 Completed - Urinary Calculi Clinical Trials

Analysis the Relationship Between the Abdomen CT and Outcomes in Acute Urinary Stone Patients

Start date: January 2011
Phase: N/A
Study type: Observational

This is an observational study based on retrospectively collected data of ureter stone patients between 2011 and 2014. Aim of study is to determine radiologic findings of non-contrast abdominal computerized tomography as predicting clinical outcomes of suspect ureter stone patients in emergency department (ED).

NCT ID: NCT02725281 Completed - Pain Clinical Trials

Pain and Anxiety During Extracorporeal Shock Wave Lithotripsy

Start date: April 2014
Phase: N/A
Study type: Interventional

Investigators observed that during the Extracorporeal Shock Wave Lithotripsy (ESWL) non-pharmacological methods used for reducing the level of the pain and anxiety among the patients with the urinary stones are not sufficient and the effectiveness of these methods is controversial. There are very few studies, which investigated the effects of music on the pain and anxiety during ESWL. In addition, any randomized clinical trial related to the use of stress ball for relaxation and distraction on the reduction of pain and anxiety during lithotripsy has not been found in the relevant literature. Investigators also evaluated that further evidence-based studies are necessary. Thus, investigators aimed to investigate the effectiveness of stress ball and music for reducing the pain and anxiety of the patients during ESWL in this study.

NCT ID: NCT02539004 Completed - Urolithiasis Clinical Trials

US-Non Contrast Computed Tomography Real-time Fusion for Urinary Stones Follow up

Start date: June 2015
Phase:
Study type: Observational

Urolithiasis is a universal problem, a large part of patients will be affected by multiple stones throughout their lifetime, with estimated recurrence rates of 75% within 20 years. The high recurrence rate requires an increasing amount of imaging follow-up. US-NCCT real-time fusion (Fusion) enables lesion assessment and follow up using both modalities as reference for each other. Our study proposes a novel approach for short term follow up of patients using Fusion instead of repeat NCCT exams. the goal of the study is to create an initial proof of concept that Fusion is effective for follow up of known urinary stones. the study is a prospective study on Patients with an obstructing ureteral stone found on a NCCT. Patients will undergo Fusion (using General Electric Logiq E9) after NCCT. The primary endpoint was the ability to locate the ureteral stone using US with guidance of the NCCT as a "Road Map".

NCT ID: NCT02188108 Completed - Urolithiasis Clinical Trials

Validation of the Wisconsin Stone-QOL

Start date: July 2014
Phase: N/A
Study type: Interventional

The overall purpose of this study is to evaluate criterion-related validity of a newly-developed disease-specific instrument to assess the health-related quality of life (HRQOL) of patients who have had kidney stones. Specific aims of this study are: 1. Aim 1. Evaluate the population/external validity (generalizability) of the Wisconsin Stone-QOL by answering the question, "Is the Wisconsin Stone-QOL useful for assessing the HRQOL of patients who form kidney stones from a broad region of North America?" 2. Aim 2. Assess the ability of the Wisconsin Stone-QOL to detect changes within patients related to stone interventions and other disease-specific outcomes by answering the question, "Is the Wisconsin Stone-QOL sensitive to changes in stone-related outcomes within individuals?"

NCT ID: NCT02187614 Completed - Renal Colic Clinical Trials

Efficacy Study of Different Analgesic Options in Kidney Stone Pain Management

Start date: August 2014
Phase: Phase 4
Study type: Interventional

Abdominal pain is one of the most common presentations to an emergency department (ED). Among patients presenting with abdominal pain, a common diagnosis in the Middle East is renal colic (urolithiasis or Kidney stones). As the patients with renal colic writhe around in agonizing pain, the first priority in an ED from a patient's perspective is fast and safe analgesia and to be pain free as early as possible. There are variations in physician preference to choose initial analgesic drug for managing such pain. Commonly used drugs are: - Opioids such as Morphine or Fentanyl - Non steroidal drugs such as Diclofenac, Ketorolac or Brufen - and Paracetamol intravenous injection. A robust evidence in comparison of diclofenac versus morphine and paracetamol is lacking. This study is design to obtain data on efficacy of these three drugs within 30 minutes in a non inferiority trail.

NCT ID: NCT02140970 Completed - Urolithiasis Clinical Trials

Randomized Trial of NSAID vs Placebo Prior to Ureteral Stent Removal

Start date: May 2014
Phase: N/A
Study type: Interventional

This study plans to learn more about whether ibuprofen can reduce pain after removal of a ureteral stent more than a placebo. Some patients experience pain after removal of a ureteral stent. The investigators plan to learn how often this occurs and whether it can be prevented. The investigators hypothesize that children who have a temporary, indwelling ureteral stent will experience a significantly less post-operative pain if given a non-steroidal anti-inflammatory (NSAID) prior to removal of the ureteral stent when compared to placebo. The investigators hypothesize that the incidence of severe post-stent removal pain is similar to an adult population.

NCT ID: NCT01539265 Completed - Urinary Calculus Clinical Trials

A Dose-finding Study of Silodosin in Patients With Urinary Calculi

Start date: n/a
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy and the safety of silodosin in urinary calculi patients.

NCT ID: NCT01222325 Completed - Clinical trials for Urinary (Renal or Ureteral) Stones

Comparison Between Two Shock Wave Regimens for Treating Urinary Stones

Start date: June 2008
Phase: N/A
Study type: Interventional

In order to check if a reduction in the frequency and total number of shocks delivered during extracorporeal shockwave lithotripsy (SWL) results in a great number of stone-free patients,the investigators compared two different ways of treating urinary stones using SWL.

NCT ID: NCT01144949 Completed - Urolithiasis Clinical Trials

Study of Silodosin to Facilitate Passage of Urinary Stones

Start date: June 2010
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess if patients treated with silodosin will have a higher spontaneous passage rate of their ureteral stone than those treated with placebo.

NCT ID: NCT00857090 Completed - Kidney Stones Clinical Trials

Pharmacokinetic, Safety and Efficacy Study of OMS201 in Subjects Undergoing Retrograde Ureteroscopic Removal of Upper Urinary Tract Stones

Start date: March 2009
Phase: Phase 1/Phase 2
Study type: Interventional

The objectives of the study are to assess the systemic exposure, safety and efficacy of three concentrations of OMS201 in subjects undergoing retrograde ureteroscopic removal of upper urinary tract stones.