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Urinary Bladder, Overactive clinical trials

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NCT ID: NCT03322748 Not yet recruiting - Multiple Sclerosis Clinical Trials

Efficacy of Lower Limb Exercises on Overactive Bladder Symptoms in Patients With Multiple Sclerosis

Start date: February 2018
Phase: N/A
Study type: Interventional

The aim of the study (OVERACT_V1) is to verify if the isometric contraction of ankle plantarflexor and Hamstring muscles, induces a significant reduction of overactive bladder symptoms in patients with Multiple sclerosis.

NCT ID: NCT03280316 Not yet recruiting - Overactive Bladder Clinical Trials

Efficacy Comparison Between Different Management Strategies for Consistent OAB in Patients With SVMs After Surgery

Start date: January 2023
Phase: N/A
Study type: Interventional

The investigators' goal is to compare the efficacy of three different management strategies (sacral neuromodulation, botulinum toxin, M receptor antagonist) in treating consistent OAB in patients with SVMs after surgery.

NCT ID: NCT03260907 Not yet recruiting - Overactive Bladder Clinical Trials

Efficacy and Safety of Electroacupuncture and Acupuncture in Postmenopausal Women With Overactive Bladder

Start date: March 2, 2018
Phase: N/A
Study type: Interventional

The purpose of this study is to verify the efficacy and safety of electroacupuncture treatment of postmenopausal women with overactive bladder (OAB).

NCT ID: NCT03238053 Not yet recruiting - Breast Cancer Clinical Trials

Laser Treatment of Genito-urinary Syndrome in Women

Start date: October 1, 2022
Phase: N/A
Study type: Interventional

Women with genitourinary syndrome of menopause, overactive bladder, with breast or endometrial cancer are randomized to either laser treatment og sham treatment for 3 months. The randomization is stratified for estrogen treatment. The effect is evaluated by questionnaire, histology and microbiology swaps

NCT ID: NCT03061760 Not yet recruiting - Prostate Cancer Clinical Trials

Effects of Urinary Bladder Hypertrophy on Urge Urine Incontinence After Radical Prostatectomy

Start date: March 1, 2017
Phase: N/A
Study type: Observational

This study is designed to evaluate men before radical prostatectomy for the incidence of Overactive Bladder (OAB), as well as urge urine incontinence (UUI) development after the surgery. Patients will be evaluated for signs of OAB and for signs of Bladder Outlet Obstruction (BOO). Afterwards they will be divided into four observational groups. Follow up period is designed to be 12 months.

NCT ID: NCT02980328 Not yet recruiting - Clinical trials for Urinary Incontinence

Low-level Light Therapy for Overactive Bladder and Urinary Incontinence

Start date: December 2016
Phase: Phase 3
Study type: Interventional

This study aims to evaluate the effectiveness of a self-therapeutic approach of skin adhesive low-level light therapy (LLLT) in females with Overactive Bladder (OAB) and Urinary Incontinence (UI)

NCT ID: NCT02946723 Not yet recruiting - Clinical trials for Refractory Overactive Bladder

A Study to Compare the Efficacy and Safety of Ultrasound Guided Lead Implantation for Sacral Neuromodulation (SNM) in Subjects With Overactive Bladder (OAB) With X-Ray Guided Technique

Start date: February 2017
Phase: Phase 1
Study type: Interventional

Overactive bladder(OAB,Urgency) was determined by International Continence Society as Urinary urgency, usually accompanied by frequency and nocturia, with or without urgency urinary incontinence, in the absence of urinary tract infection (UTI) or other obvious pathology.The SNM treatment involves a two-stage surgical procedure performed under local anesthesia. The device include IPG (implantable programme generator) and lead. In the initial test phase, 1st stage, electrode is placed near the sacral nerve and requires a 2 weeks assessment. This allows your doctors and you to assess your initial response according to your voiding dairy and satisfaction. In 2nd stage, SNM procedure is implantation of the IPG. X ray guidance is harmful to both patients and doctors, while ultrasound guidance is real time visual guidance ,easy to operate by doctors and a radiation free option to challenge anatomy. Urologists are skilled in both ultrasound operations and anatomy basics and dedicating to developing better guidance technique in surgery. The study here compare the efficacy and safety of ultrasound versus X ray guidance technique in SNM.

NCT ID: NCT02821312 Not yet recruiting - Overactive Bladder Clinical Trials

A Study to Evaluate Safety, Tolerability and Pharmacokinetics of DA-8010 in Healthy Subjects

Start date: June 2016
Phase: Phase 1
Study type: Interventional

This study is a Phase I, Randomised, Double-Blind, Placebo-Controlled, Dose-Escalation Study to Evaluate Safety, Tolerability and Pharmacokinetics After Single and Multiple Oral Administration of DA-8010 in Healthy Subjects.

NCT ID: NCT02704013 Not yet recruiting - Overactive Bladder Clinical Trials

Urinary Biomarkers in Overactive Bladder in Children

Start date: April 2016
Phase: N/A
Study type: Interventional

It is a single-center, prospective, interventional, single-arm study. Aim is to investigate which variables are significantly correlated with prolonged anticholinergic treatment (>6 months) in children with overactive bladder (OAB). Investigated variables will include urinary neurotrophins and inflammatory cytokines, sonographic biomarkers, symptom score scale, demographics, and urodynamic findings. Secondary aim is to analyze sensitivity and specificity of urinary biomarkers in diagnosis and management of OAB compared to urodynamics and treatment outcome.

NCT ID: NCT02477241 Not yet recruiting - Clinical trials for Urinary Bladder, Overactive

Brain Areas Involved in Bladder Filling and Contraction

Start date: September 2015
Phase: N/A
Study type: Interventional

Overactive Bladder syndrome (OAB) is a medical condition with symptoms of urgency, with or without incontinence, usually with frequency and nocturia, with no proven infection or obvious pathology 1. This study will explore the relationship between OAB, obstruction and the micro contractions as well as the brain areas involved in both normal desire to void and urgency, gaining a better understanding of the bladder pathophysiology and in the future allowing better strategy of treatment options for patients suffering from OAB.