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Clinical Trial Summary

New types of biologics have brought advantages in therapy strategies for Crohn's disease. However, clinical data evaluating their efficacy and adverse in China is lacking. We aimed to evaluate the short-term and long-term therapeutic effect as well as drug adverse of Ustekinumab (UST) and Vedolizumab (VED). Besides, we aim to figure out the independent factors predicting the effectiveness of new biologics. Relations between drug exposure (trough concentration and antibody concentration) and therapeutic efficacy are study in-depth by this retrospective observational study.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04923100
Study type Observational
Source Sixth Affiliated Hospital, Sun Yat-sen University
Contact Jiayin Yao
Phone 13826462890
Email yjyin3@mail.sysu.edu.cn
Status Recruiting
Phase
Start date June 10, 2021
Completion date March 29, 2025

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