Therapeutic Effect of New Biologics in Crohn's Disease

Status Recruiting

Clinical Trial Summary

New types of biologics have brought advantages in therapy strategies for Crohn's disease. However, clinical data evaluating their efficacy and adverse in China is lacking. We aimed to evaluate the short-term and long-term therapeutic effect as well as drug adverse of Ustekinumab (UST) and Vedolizumab (VED). Besides, we aim to figure out the independent factors predicting the effectiveness of new biologics. Relations between drug exposure (trough concentration and antibody concentration) and therapeutic efficacy are study in-depth by this retrospective observational study.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04923100
Study type	Observational
Source	Sixth Affiliated Hospital, Sun Yat-sen University
Contact	Jiayin Yao
Phone	13826462890
Email	yjyin3@mail.sysu.edu.cn
Status	Recruiting
Phase
Start date	June 10, 2021
Completion date	March 29, 2025

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