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NCT ID: NCT00012597 Completed - Pressure Ulcers Clinical Trials

Pressure Ulcer Assessment Via Telemedicine

Start date: n/a
Phase: N/A
Study type: Interventional

A Web-based telemedicine system for monitoring the status of patients with pressure ulcers has been developed. It consists of three major data collection components: (1) digital photograph of ulcer; (2) quantitative measurements of wound status (i.e., ulcer area and volume, skin elasticity); and (3) other wound and patient data collected by a nurse. Data are collected via laptop computer and transmitted to a central database, where a computer program transforms the data into the necessary reporting format. The output is posted onto a World Wide Web page for access by the consulting physician. The system incorporates all data requirements for assessment recommended by AHCPR's Clinical Practice Guideline, Treatment of Pressure Ulcers.

NCT ID: NCT00011531 Completed - Clinical trials for Diabetic Foot Ulcers

Investigation of Subatmospheric Pressure Dressing on Pressure Ulcer Healing

Start date: January 2000
Phase: Phase 2
Study type: Interventional

Many spinal cord injury (SCI) and otherwise debilitated patients develop pressure ulcers over the course of their injury or disease. Despite enhanced wound care management, many pressure ulcers do not heal completely and require surgical myocutaneous rotational flap coverage. Even then they often recur. The objectives of this study are: (1) to conduct a controlled comparative study of the effectiveness of subatmospheric pressure dressing (SPD) in healing pressure ulcers versus conventional saline wet-to-moist dressing techniques; (2) to establish indications and contra-indications for use of SPD In treating pressure ulcers; and (3) to develop a noninvasive, clinically usable optical digitizer and associated software for measurement of wound geometry for standardized quantitative assessment and longitudinal monitoring of wound healing.

NCT ID: NCT00006426 Completed - Diabetes Mellitus Clinical Trials

Achilles Tendon Lengthening in Patients With Diabetes to Prevent Foot Ulcers

Start date: August 1998
Phase: Phase 1
Study type: Interventional

People with diabetes often develop severe skin problems (ulcers) on their feet. Sometimes these are treated with surgery and other times by temporarily immobilizing the foot in a cast. This study compares the effect of surgery to lengthen the Achilles tendon and put the foot in a cast, to using a cast alone. The study will also examine how foot strength, joint movement, and overall ability to walk, balance and climb stairs is affected.

NCT ID: NCT00004810 Completed - Ulcerative Colitis Clinical Trials

Phase II Placebo-Controlled Study of 4-Aminosalicylic Acid for Ulcerative Colitis

Start date: June 1996
Phase: Phase 2
Study type: Interventional

OBJECTIVES: I. Assess the safety and efficacy of 4-aminosalicylic acid in patients with mildly to moderately severe ulcerative colitis.

NCT ID: NCT00004412 Completed - Sickle Cell Anemia Clinical Trials

Phase II Randomized Trial:Arginine Butyrate Plus Standard Local Therapy in Patients With Refractory Sickle Cell Ulcers

Start date: September 1997
Phase: Phase 2
Study type: Interventional

OBJECTIVES: I. Compare the efficacy of local care alone vs local care plus arginine butyrate in terms of healing rate in patients with refractory sickle cell ulcers. II. Determine the effect of arginine butyrate therapy on tissue factors related to promotion or inhibition of wound healing in these patients. III. Determine whether the regimen used in this study is appropriate for testing in pivotal trials.