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MAD Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PB-119 to Subjects With T2DM

Type2 Diabetes Mellitus Clinical Trial

Official title:
A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Sequential Parallel Group, MAD Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PB-119 to Subjects With T2DM

Clinical Trial Summary

This was a phase 1, randomized, double-blind, placebo-controlled, sequential parallel group, MAD study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of four once-weekly subcutaneous doses of PB-119 to subjects with T2DM.

Clinical Trial Description

Dose levels of 25 µg, 50 µg, 100 µg and 200 µg with a dosing regimen of once weekly for 4 consecutive weeks will be evaluated ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03072407
Study type Interventional
Source PegBio Co., Ltd.
Contact
Status Completed
Phase Phase 1
Start date November 24, 2015
Completion date November 15, 2016
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