Prediction Models for Postoperative Reintubation in Patients With Acute Aortic Dissection

Type A Aortic Dissection Clinical Trial

— ADreintubate  

Official title:

Multiple Automated Machine-learning Prediction Models for Postoperative Reintubation in Patients With Acute Aortic Dissection

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT06415630
• Other study ID #: WHUH-AADreintu
• Status: Completed
• Start date: January 1, 2018
• Est. completion date: December 31, 2023

Study information

• Verified date: May 2024
• Source: Wuhan Union Hospital, China
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Reintubation is an adverse postoperative complication in patients with Type A aortic dissection (AAD) that correlates to poor outcomes. This study aims to analyze the risk factors associated with reintubation and to create a fully automated score model to predict the incidence of reintubation. A total of 861 patients diagnosed with AAD and undergoing surgical procedures in a single institution between January 2018 and October 2023 were selected in wuhan Union Hospital. Preoperative and postoperative informmation was used for seeking risk factors and build prediction model for postoperative reintubation. Finally, 5 risk factors wasidentified and a nomogram was established for predicting postoperative reintubation in patients with AAD.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 861
• Est. completion date: December 31, 2023
• Est. primary completion date: October 31, 2023
• Gender: All
• Age group: 19 Years to 90 Years

Eligibility

Inclusion Criteria:

(1) patients diagnosed with AAD admitted for open surgery; (2) aged 18 years or older.

Exclusion Criteria:

(1) patients deceased during or within 24 hours after surgery; (2) patients with preoperative intubation.

Related Conditions & MeSH terms

• Aortic Dissection
• Type A Aortic Dissection

Intervention

Procedure:
• Type A aortic dissection surgery
Patients with type A aortic dissection undergone surgery.

Locations

Country	Name	City	State
China	Union Hospital, Tongji Medical College, Huazhong University of Science and Technology	Wuhan	Hubei

Sponsors (1)

Lead Sponsor	Collaborator
Wuhan Union Hospital, China

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	postoperative reintubation	reintubation incidence in patients with type A aortic dissection undergoing surgery	3 month