Type 2 Diabetes Clinical Trial
Official title:
Sequences of Aerobic and Resistance Exercise in Training and Their Effects on Cardio-metabolic Functions Among Type 2 Diabetes Patients - a Randomized Study
Aerobic exercise and resistance exercise are two types of exercise commonly used in physical conditioning. Compared to aerobic exercise, a combination of aerobic and resistance exercise has been linked to a greater reduction in hemoglobin A1c (HbA1c) among patients with type 2 diabetes (T2D). However, it is not clear that in a concurrent aerobic-resistance training session, whether the orders of the two types of exercise could act differently in glucose metabolism. This pilot randomized trial aims to investigate the effect of the sequence of exercise modalities (aerobic-resistance vs resistance-aerobic in a training session) on glycemic control among T2D patients following an 8-wk intervention period. The trial also aims to compare the effects of the two different sequences in blood pressure, sleep quality, and lower limb muscle strength among the T2D population.
Objectives: This pilot randomized study aims to explore the effects of aerobic and resistance training sequences on glycemic control among type 2 diabetes (T2D) patients through an 8-wk combined aerobic and resistance exercise training program. The secondary objectives are to compare the effects of different training sequences on blood pressure, sleep quality, and lower limb muscle strength in type 2 diabetes over the 8-wk intervention period. Study Population: A total of 60 participants with T2D aged 40-70 years (sex ratio approximately 1:1) with a course of type 2 diabetes of more than one year are included. Participants are residents of Nanjing Municipality, Jiangsu Province, China. Participants are recruited through printed advertisement delivered at Maigaoqiao Community Health Service Center, Qixia District, Nanjing, or via online advertisement published on the official social media (WeChat) channels of the Health Service Center. Randomization: Participants are stratified by baseline hemoglobin A1c (HbA1c) and age, they are randomly assigned into two groups with a block size of six. The study groups are: 1) aerobic before resistance training (AR group, n=30); 2) resistance before aerobic training (RA group, n=30). ;
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