Pre-dinner vs. Post-dinner Exercise on Glycemic Control

Type 2 Diabetes Clinical Trial

Official title:

Exercise Timing and Postprandial Glycemia in Type 2 Diabetes

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02180620
• Other study ID #: exertime
• Status: Completed
• Phase: N/A
• First received: June 30, 2014
• Last updated: June 6, 2017
• Start date: September 2013
• Est. completion date: April 2014

Study information

• Verified date: June 2017
• Source: University of Missouri-Columbia
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

With many medications we prescribe them relative to time of day or a meal. This study established if pre dinner vs post dinner exercise was more effective at altering post dinner glucose and triglyceride levels vs no exercise at all.

Description:

All participants completed three trials in a random order in which they consumed a standardized dinner meal with 1) no RE (NoRE), 2) pre-dinner RE (RE→M), and 3) post-dinner RE beginning 45 min after dinner (M→RE). Diet was standardized during the day of testing. Participants reported to the lab for testing sometime between 3 - 5:30 p.m. and upon arrival a venous catheter was inserted into a forearm vein. Frequent blood sampling, indirect calorimetry measurements, and subjective well-being measurements ensued for ~5.75 h while the participants were in the lab.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 13
• Est. completion date: April 2014
• Est. primary completion date: April 2014
• Accepts healthy volunteers: No
• Gender: All
• Age group: 25 Years to 55 Years

Eligibility

Inclusion Criteria:

• Obese ( body mass index 30-45 kg/m2)

• Physician diagnosed with type 2 diabetes receiving standard medical care

• Non-smokers

• Pregnancy

• Lactating mothers

Exclusion Criteria:

• Insulin

• Surgical weight loss

• Orthopedic limitations to exercise

• Weight loss in the previous 3 months

Related Conditions & MeSH terms

• Diabetes Mellitus, Type 2
• Type 2 Diabetes

Intervention

Other:
• No exercise
During the no exercise trial (NoEX), the participants will remain sedentary during testing.
• Meal then exercise
During the post-meal exercise trial (M?EX), 45 min of resistance training will be performed
• exercise then meal
During the exercise prior to the meal trial (EX?M), 45 min of resistance training will be performed

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
University of Missouri-Columbia

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	GLP-1 concentrations		Blood samples were taken every 5-10 min during the first 3.7 h of testing and every 30 min during the last 2 h
Primary	glucose concentrations		Blood samples were taken every 5-10 min during the first 3.7 h of testing and every 30 min during the last 2 h
Secondary	triglyceride concentrations		Blood samples were taken every 5-10 min during the first 3.7 h of testing and every 30 min during the last 2 h