Type 2 Diabetes Clinical Trial
Official title:
Metformin, Exenatide, and Glargine Insulin in Combination for Treatment of Patients With Type 2 Diabetes
This study is designed to look at how using glargine insulin with oral diabetes medications
and exenatide may improve control of blood sugar levels and weight gain in type 2 diabetics.
The main study will last 32 weeks. However, all participants completing 32 weeks will be
invited to continue for another 24 weeks taking the insulin and oral medication and
exenatide treatment. This extension comparing insulin and oral medication with insulin and
oral medication and exenatide will look at the long term weight loss/gain and blood sugar
level control effects of this new drug regimen.
There is also a sub-study in the Clinical Research Center (CRC), which requires two 38-hour
inpatient stays during the main study. This study offers the opportunity to study 24-hour
blood sugar and metabolic patterns quantitatively.
n/a
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment
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