Type 2 Diabetes Mellitus Clinical Trial
Official title:
A Double-Blind Randomised Controlled Trial Investigating the Acute Effects of Mycoprotein on Glycaemic Control and Appetite in South Asian and Caucasian Adults With Type 2 Diabetes Mellitus
Diet is the cornerstone treatment to manage blood sugar in people with Type 2 Diabetes (T2D).
Fibres like guar gum and protein are macronutrients that have an effect in blood sugar
levels. Mycoprotein is a fungi-based food high in both dietary fibre and protein shown to
have a role in regulating blood sugar levels in healthy. However, little is known about the
effects of mycoprotein on blood sugar levels in people with T2D. We are interested in South
Asian because they have a different blood sugar response to the same food than a Caucasian.
The main aims of the study is to assess:
- The effect of mycoprotein in different formats (soup or mince) in blood sugar levels and
appetite in South Asian and Caucasian with Type 2 Diabetes.
- The effect of the combination of mycoprotein with guar gum in different formats (soup or
mince) in blood sugar levels and appetite in South Asian and Caucasian with T2D.
This is a double-blind crossover RCT. A total of 48 participants (24 Caucasian and 24 South
Asian) with T2D and non insulin treated will be recruited. Participant will be randomly
allocated to one of these two groups:
Group 1: Test food in form of soup and Group 2: Test food in form of mince. Once allocated in
one of the groups, participant will consume in a random order 6 different test foods (soy,
chicken, mycoprotein with and without guar gum) in a determined format (either as in soup or
mince).
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