Type 2 Diabetes Mellitus Clinical Trial
Official title:
Beneficial Effects of Exercise Training on Physical Capacity in Type 2 Diabetics: Improvement in Skeletal Muscle Energetic Capacity, Endothelial Dysfunction and Glycemic Control
| Verified date | September 2017 |
| Source | University Hospital, Strasbourg, France |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | |
| Study type | Interventional |
The aim of this study is to evaluate the improvement in skeletal muscle energetic capacity, endothelial dysfunction and glycemic control induced by physical training in 20 sedentary patients with a type 2 diabetes.The protocol consists in a physical training program with 3 sessions of 30 minutes per week during six consecutive weeks. A skeletal muscle biopsy, a cardiac and humeral artery ultrasounds, a glycemic and tensional holters will be performed before and at the end of the physical training program.
| Status | Terminated |
| Enrollment | 15 |
| Est. completion date | August 2014 |
| Est. primary completion date | August 2014 |
| Accepts healthy volunteers | No |
| Gender | All |
| Age group | 40 Years to 70 Years |
| Eligibility |
Inclusion Criteria: - sedentary adult with type 2 diabetes - BMI between 25 and 35 kg/m² - Hba1c < 10 % Exclusion Criteria: - unstable coronary artery disease - advanced peripheral occlusive arterial disease - proteinuria > 3 g/d and / or creatinine clearance < 30 ml / mn - advanced diabetic neuropathy |
| Country | Name | City | State |
|---|---|---|---|
| France | Médecine Interne et Nutrition, Hôpital Civil, Hôpitaux universitaires de Strasbourg | Strasbourg | |
| France | Service de Médecine Interne et Nutrition, Hôpital de Hautepierre, Hôpitaux universitaires de Strasbourg | Strasbourg | |
| France | Service de Physiologie et d'Explorations Fonctionnelles, Nouvel Hôpital Civil, Hôpitaux universitaires de Strasbourg | Strasbourg |
| Lead Sponsor | Collaborator |
|---|---|
| University Hospital, Strasbourg, France |
France,
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