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Liraglutide as Additional Treatment to Insulin in Patients With Autoimmune Diabetes Mellitus

Type 1 Diabetes Mellitus Clinical Trial

Official title:
Effect of Liraglutide as Additional Treatment to Insulin in Patients With Autoimmune Diabetes Mellitus

Clinical Trial Summary

The purpose of this study is to investigate the therapeutic effect of Liraglutide on autoimmune diabetes.

Clinical Trial Description

Autoimmune Diabetes Mellitus (AIDM) is a subtype of diabetes mellitus caused by autoimmune destruction of beta cells in the islet, including Type 1 diabetes and Latent Autoimmune Diabetes in Adults (LADA). Insulin has been used as a routine therapy for AIDM to alleviate the hyperglycemic status, yet cannot effectively prevent the progressing destruction of beta cells or preserve its function. Glucagon-like peptide (GLP-1) analog Liraglutide has been tested in large-scale clinical trial to prove its various benefits for beta cells and glucolipid metabolism in Type 2 diabetes and obesity patients. However, its clinical application in AIDM is not well-defined so far. The aim of this study is to investigate the potential use of Liraglutide on glycemic control in AIDM. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03011008
Study type Interventional
Source Second Xiangya Hospital of Central South University
Contact Zhiguang Zhou, MD/PhD
Phone 86-731-85292154
Email zhouzg@hotmail.com
Status Recruiting
Phase Phase 4
Start date January 2017
Completion date June 2021
View Details
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