Turner Syndrome Prenatal Diagnosis Study

Status Recruiting

Clinical Trial Summary

The goal of this study is to compare the features of Turner syndrome in girls who are diagnosed before birth because of fetal concerns versus those who are diagnosed when their mother has an amniocentesis for another reason.

Clinical Trial Description

This is an observational study which will look at girls who are diagnosed with Turner syndrome before they are born. Girls will be divided into two groups: 1) those diagnosed because of features seen on ultrasound which raised the question of Turner syndrome and 2) those diagnosed incidentally when their mother had an amniocentesis for another reason such as advanced maternal age.

No clinical procedures nor interventions will be done as part of this data collection study which will occur for the first 3 to 6 years of the girl's life. The investigators will be looking to see if girls who are diagnosed incidentally have less features of Turner syndrome than those girls who are diagnosed because of fetal ultrasound. ;

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01668251
Study type	Observational
Source	Seattle Children's Hospital
Contact	Patricia Fechner, MD
Phone	206-987-5037
Email	patricia.fechner@seattlechildrens.org
Status	Recruiting
Phase	N/A
Start date	January 2006
Completion date	January 2017

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT01734486` - Growth Response in Girls With Turner Syndrome	Phase 4
Completed	`NCT01678261` - X-chromosome Inactivation, Epigenetics and the Transcriptome	N/A
Completed	`NCT01419249` - First Year Growth Response Associated Genetic Markers Validation Phase IV Open-label Study in Growth Hormone Deficient and Turner Syndrome Pre-pubertal Children: the PREDICT Pharmacogenetics Validation Study	Phase 4
Completed	`NCT01518036` - Use of Somatropin in Turner Syndrome	Phase 3
Recruiting	`NCT04948658` - Gonadal Tissue Freezing for Fertility Preservation in Individuals at Risk for Ovarian Dysfunction, Premature Ovarian Insufficiency and Clinically Indicated Gonadectomy
Completed	`NCT01563926` - Evaluating Acceptance of New Liquid Somatropin Formulation in Children With Growth Hormone Deficiency	Phase 3
Completed	`NCT02787486` - Expanded Noninvasive Genomic Medical Assessment: The Enigma Study
Completed	`NCT00877942` - Sex Differences in Early Brain Development; Brain Development in Turner Syndrome	N/A
Completed	`NCT00825617` - Quantitative Liver Functions in Turner Syndrome With and Without Hormone Replacement Therapy	N/A
Recruiting	`NCT04463316` - GROWing Up With Rare GENEtic Syndromes
Enrolling by invitation	`NCT03836300` - Parent and Infant Inter(X)Action Intervention (PIXI)	N/A
Completed	`NCT01245374` - Norditropin NordiFlex® Device Compared to the Device Previously Used by Patients or Parents	Phase 4
Completed	`NCT01322165` - National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions	N/A
Terminated	`NCT00419107` - Beta Cell Function in Women With Turner Syndrome	N/A
Active, not recruiting	`NCT00625001` - Long Term Follow-up of Bone Mineral Density in Hormone Treated Turner Syndrome	N/A
Completed	`NCT00029159` - The Effect of Androgen and Growth Hormone on Height and Learning in Girls With Turner Syndrome	Phase 3
Completed	`NCT01518062` - Safety of Somatropin and Induction of Puberty With 17-beta-oestradiol in Girls With Turner Syndrome	Phase 4
Completed	`NCT00471731` - Dry Eye in Women With Turner Syndrome and Women With Premature Ovarian Failure	N/A
Completed	`NCT00256126` - Predictive Markers in Growth Hormone Deficiency (GHD) and Turner Syndrome (TS) Children Treated With SAIZEN®	Phase 4
Completed	`NCT03181230` - Health, Fitness, and Quality of Life in Adolescent Girls With Turner Syndrome