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Multimodal Connectome Study of Brain Tumor-operated Patients — ConnecTC  

Tumor, Brain Clinical Trial

Official title:
Multimodal Connectome Study of Brain Tumor-operated Patients

Clinical Trial Summary

In this pilot study, the investigators propose a multimodal evaluation of the brain connectivity of brain tumor patients, in order to better understand the effects induced by focal lesions on brain structure and function, as well as brain plasticity mechanisms that may occur in such condition. The investigators aim at drawing a multimodal brain connectivity map of focally brain-damaged patients, with a view to improve onco-functional neurosurgical practices.

Clinical Trial Description

Patients included in the present study will first perform the pre-operative MRI (dMRI and fMRI) with a specific High Resolution Angular Diffusion (HARDI) sequence and a functional acquisition at rest. Then, the investigators will record their cortico-cortical evoked potentials elicited by direct electrostimulation during the surgery, just before the tumor removal, following our usual protocol. Finally, all data (clinical, diffusion, electrical and functional connectivity) will be processed and correlated to each other. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04163315
Study type Interventional
Source Centre Hospitalier Universitaire de Nice
Contact Fabien ALMAIRAC, MD, PhD
Phone 04 92 03 85 57
Email almairac.f@chu-nice.fr
Status Recruiting
Phase N/A
Start date December 12, 2019
Completion date September 2024
View Details
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