Tropical Spastic Paraparesis Clinical Trial
Official title:
Effect of Raltegravir in Patients With Myelopathy/Tropical Spastic Paraparesis Associated With Infection by Human T-Lymphotropic Virus 1 (HTLV-1). Pilot Study
This is a pilot study of intervention in a group of patients with tropical spastic paraparesis/ myelopathy to evaluate virologic and clinical response of raltegravir plus zidovudine in this group of patients.
The study will the investigators develop in The Tropical Medicine Institute Alexander von
Humboldt that is a referral center in Peru for diseases associated to Human T-Lymphotropic
Virus 1 Infection (HTLV-1). The Institute has a cohort of around 600 patients currently being
followed up and around 20 to 25 new patients are admitted every year with this disease.
This is a pilot study of intervention in a group of patients with tropical spastic
paraparesis/ myelopathy to evaluate virologic and clinical response of raltegravir plus
zidovudine in this group of patients on the follow-up of 48 weeks.
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