Treatment Resistant Depression Clinical Trial
Official title:
Role Of Ketamine in Treatment-Resistant Major Depressive Disorder And Its Effect on Suicidality
In this study we will assess the effect of Ketamine infusion on depressive symptoms and in particular its effect on Suicidal behavior, ideation and thoughts in patients with treatment- resistant MDD.
A Twice repetition of IV infusion of 0.5 mg/kg of ketamine produces an antidepressant
response in individuals with treatment-resistant MDD
The work aims to:
1. To assess the onset of action and degree of improvement and the duration of
antidepressant effect of ketamine in a sample of patients with treatment -resistant
major depressive disorder.
2. To find out whether the onset of Ketamine antidepressant effect is associated with an
improvement of suicidality in those patients.
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