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NCT05182619 Clinical Trial

Stellate Block Versus Nimodipine Infusion for Traumatic Brain Injury

Traumatic Brain Injury Clinical Trial

Official title:
Ultrasound-guided Stellate Ganglion Block Versus Nimodipine Infusion for Enhancement of Cerebral Blood Flow in Traumatic Brain Injury

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT05182619
Other study ID # soh-Med-21-12-19
Secondary ID
Status Not yet recruiting
Phase Early Phase 1
First received
Last updated
Start date January 1, 2022
Est. completion date April 1, 2023

Study information
Verified date December 2021
Source Sohag University
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

the study is designed to perform an intervention for enhancement of cerebral blood flow in patients with traumatic brain injury showing vasospasm through transcranial doppler

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 60
Est. completion date April 1, 2023
Est. primary completion date January 1, 2023
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - patients more than 18 ys old with isolated head trauma and traumatic brain injury Exclusion Criteria: - • Hemodynamic instability (mean ABP less than 70 mmHg) - History of severe systemic disease including cardiopulmonary failure or hepatorenal failure - Allergy to local anesthetics - Coagulation disorders - Abnormal neck structures disturbing normal anatomy as neck tumors

Study Design

Related Conditions & MeSH terms

Intervention

Procedure:
• ultrasound-guided stellate ganglion block
under aseptic conditions, using the ultrasound guidance, bilateral stellate ganglion block will be done using bupivacaine and betamethasone mixture, 8 ml volume will be given for each side

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Sohag University

Outcome
Type Measure Description Time frame Safety issue
Primary enhancement of cerebral blood flow increased blood flow through middle cerebral artery and basilar artery measured by transcranial doppler ultraound one week
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