Fibrinogen Concentrate in Isolated Traumatic Brain Injury

Status Recruiting

Clinical Trial Summary

Fibrinogen is a unique precursor of fibrin and cannot be compensated for by other coagulation factors. If plasma fibrinogen concentrations are insufficient, hemostatic clots cannot be formed with the appropriate firmness. In severe traumatic brain injury(TBI) patients, plasma fibrinogen concentrations decrease earlier and more frequently than other coagulation factors,predicting massive bleeding and death.

The purpose of this study is to try early injection of fibrinogen concentrate in severe isolated traumatic brain injury and investigation the effect of it on post bleeding and complications.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03304899
Study type	Interventional
Source	Isfahan University of Medical Sciences
Contact	Mahdi Vahidian, Student
Phone	+989103374626
Email	Mehdivahid2@yahoo.com
Status	Recruiting
Phase	Phase 1/Phase 2
Start date	October 23, 2018
Completion date	January 21, 2020

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