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Tooth Loss clinical trials

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NCT ID: NCT04712565 Recruiting - Tooth Loss Clinical Trials

Hard and Soft Tissue Maintenance Around Implants With a Sloped Configuration

Start date: January 14, 2021
Phase: N/A
Study type: Interventional

This study is a controlled, randomized clinical trial over about 16-months (active phase). 40 patients in need of replacement of a single tooth with a minimal crestal bone width of 4 - 5mm and suitable for simultaneous GBR (Guided Bone Regeneration) procedure as well as at least a neighboring tooth on its mesial aspect will be consecutively recruited at the Department of Dental Medicine and Oral Health Graz. Volunteers will be screened and eligible subjects will be randomized to two different groups. In group 1 implants with regular neck design (Astra Tech Implant EV C, Dentsply Implants Manufacturing GmbH, Hanau, Germany) and GBR procedure (BioOss® and BioGide®, Geistlich, Wolhusen, Schweiz) fixed with two membrane pins (Hipp Medical AG, Kolbingen, Germany) will be used; in group 2 implants with sloped marginal configuration (Astra Tech Implant Profile EV C, Dentsply Implants Manufacturing GmbH, Hanau, Germany) without bone augmentation are used. The dimension of the bony defect and amount of lingual-buccal bone height discrepancy (max. 5mm) respectively bone width will be evaluated using a 3-D volume tomography (Planmeca ProMax® 3D Max, Planmeca, Helsinki, Finland), which is needed for digital planning (Simplant Planning Software, Leuven, Belgium) of the implant position, length and diameter as well.

NCT ID: NCT04605445 Recruiting - Pain Clinical Trials

One vs Two Visits Root Canal Treatments in Infected Teeth

Start date: November 18, 2020
Phase: N/A
Study type: Interventional

The primary aim of the study is to compare the outcome of one vs two visits endodontics (root canal treatments) performed in general dental practice of infected (necrotic) teeth, one and four years after treatment. Secondary aims are to compare the root filling quality and the frequency of complications for both treatment modalities. A pilot study will identify the shortcomings of the protocol, which will be revised accordingly. A multi-center study in several clinics from five counties throughout Sweden is planned. Consecutive eligible patients (see inclusion and exclusion criteria) with one tooth each will be included. The study sample size calculation was based on a judgement that a minimal worthwhile effect of less than 10% was not clinically relevant. The presumption was that successful outcomes would be of 75% and 65% for the different treatment arms, respectively. Three hundred and fifty six patients per group are thus needed to detect that difference as statistical significant with a power of 80% and an alfa-error of 5%. To compensate for around 30% drop-outs a number of 1000 patients will be recruited. Patients will be randomly enrolled in two arms: one in which the endodontic treatment (root canal treatment) is performed in one visit, and in the other arm in two visits. The allocation sequences for one vs multiple visit endodontics will be computer generated followed by a dark colored envelope concealed allocation. The patients will be contacted by telephone 5-7 days post-operatively, and a control visit at the clinic will be scheduled one month post-operatively to assess complications related to the treatment. A clinical control will be performed at the clinic one and four years after treatment. Intra-oral radiographs will be taken. The radiographs will be examined by two blinded and independent observers. A successful outcome is defined by clinical and radiographic normalcy. The statistical methods selected to analyse the primary outcome will be the Chi square test of 2x2 tables, or Fisher´s exact test when proportions are small and the expected value <5. The calculations will be two-tailed. Results will be considered statistically significant at p<0.05.

NCT ID: NCT04598776 Recruiting - Tooth Loss Clinical Trials

PMCF Study of CeraRoot Ceramic Implants One-piece: 1year, 5 Years Follow up

Start date: August 27, 2020
Phase:
Study type: Observational [Patient Registry]

The main objective is to evaluate the success / failure rate of CeraRoot ceramic implants (one piece) during five year follow up.

NCT ID: NCT04581304 Recruiting - Bone Loss Clinical Trials

The Use of Bio-Oss Collagen for Sinus Augmentation Using the Transcrestal Approach.

Start date: October 15, 2020
Phase: N/A
Study type: Interventional

To assess vertical bone height gain with Geistlich Bio-Oss Collagen used in conjunction with simultaneous implant installation in transcrestal approach sinus augmentation.

NCT ID: NCT04497571 Recruiting - Dental Implants Clinical Trials

Immediate Load in Dental Implants Using Conventional Drilling and Piezoelectric Osteotomy on Aesthetic Zone.

Start date: June 1, 2020
Phase: N/A
Study type: Interventional

Compare the survival rate of the implants placed using the ultrasonic technique and placed using conventional drilling, with an immediate load on the aesthetic zone.

NCT ID: NCT04377256 Recruiting - Tooth Loss Clinical Trials

Hyaluronic Acid Effect on Xenogenic Bone Healing

Start date: May 1, 2020
Phase: Phase 4
Study type: Interventional

The aim of this study is to test the hyaluronic acid hydrogel impact on the healing acceleration of xenogenic bone substitutes used in ridge preservation. Following tooth extraction, bone particles are mixed with the hyaluronic acid gel and grafted in the tooth socket. at the implant placement phase, a cone beam computer assisted tomography file is recorded in order to compare it with the baseline and a biopsy to evaluate the histological consequences.

NCT ID: NCT04265768 Recruiting - Wound Heal Clinical Trials

Soft Tissue Changes Around Dental Implants

Geistlich
Start date: June 21, 2021
Phase: N/A
Study type: Interventional

This study aims to characterize the healing pattern following soft tissue augmentation procedure concomitant to implant placement.

NCT ID: NCT04221243 Recruiting - Missing Teeth Clinical Trials

Evaluation Of Innovative 3D Printed Space Maintainer Versus Conventional One

Start date: August 1, 2019
Phase: N/A
Study type: Interventional

The primary aim of this study is to introduce a new effective and efficient 3D printed design of an intra-oral space maintainer. The secondary aim of the study is to: Evaluate the clinical performance of 3D printed space maintainer versus conventional metal band and loop over a period of 6 months regarding their functional , biological aspects and patient satisfaction.

NCT ID: NCT04153851 Recruiting - Missing Teeth Clinical Trials

Study the Effect of Neurectomy of Nasopalatine Nerve on Sensation of Anterior Palate

Start date: December 1, 2019
Phase: N/A
Study type: Interventional

Study the effect of neurectomy of nasopalatine nerve on the sensation of anterior palate in patients undergoing rehabilitation of anterior maxillary ridge with dental implant

NCT ID: NCT04120688 Recruiting - Tooth Loss Clinical Trials

3D Autotransplantation of Teeth

Start date: March 9, 2020
Phase: N/A
Study type: Interventional

The study aims to clarify the usefulness of 3D-printed replicas in association with autotransplantation of teeth in children and young adults.