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Tooth, Impacted clinical trials

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NCT ID: NCT05890040 Active, not recruiting - Clinical trials for Impacted Wisdom Teeth

Evaluation of the Effect of Watching Surgery Videos on Social Media on Anxiety Before Impacted Wisdom Tooth Extraction

Start date: July 8, 2021
Phase:
Study type: Observational

Surgical extraction of impacted wisdom teeth creates a high level of anxiety on patients. Anxiety in patients can affect the difficulty of tooth extraction, prolong the duration of surgery and increase post-operative pain. With the increasing internet usage in recent years; patients can access different information about surgical procedures by watching videos on various social media platforms in an uncontrolled manner. In the literature, the effects of impacted tooth extraction videos, which are watched by physicians before the operation, on anxiety have been examined. However, studies on the evaluation of the effect of the surgery videos watched by the patients before the surgery on their own will on anxiety and pain perception have been limited.

NCT ID: NCT05563519 Active, not recruiting - Clinical trials for Impacted Third Molar Tooth

Comparison of the Efficacy of I-Prf Impregnated Collagen and L-Prf on Healing After Impacted Third Molar Surgery

Start date: January 15, 2021
Phase: N/A
Study type: Interventional

Impacted third molar extraction is a very common surgical intervention. Post-procedure pain causes various post-operative changes such as edema and trismus. Minimizing these changes will enable patients to overcome the post-operative process more easily. In this study, it was aimed to compare the possible effects of I-PRF (Impregnated Platelet Rich Fibrin) type 1 collagen with L-PRF (Leukocyte Platelet Rich Fibrin) on postoperative complications and wound healing after lower impacted wisdom tooth surgery. There are studies in the literature showing that very different treatment methods are used for buried twenty-year-old surgery. However, although there are studies in which intra-socket L-PRF, I-PRF, and collagen plugs are applied, there is no accepted standard for comparing the effects of L-PRF and I-PRF impregnated type-1 collagen with each other or for postoperative comfort. The aim of the study is to observe the effect of 2 different techniques on postoperative complications and possible changes in wound healing and discuss whether there is a difference and the effective one.

NCT ID: NCT05067712 Active, not recruiting - Clinical trials for Embedded and Impacted Teeth

The Effect of Surgical Technique on PDC

PDC
Start date: November 25, 2017
Phase: N/A
Study type: Interventional

Permanent maxillary canines are the second teeth that most commonly assume ectopic positions after the third molars. They are diagnosed as impacted and have an incidence of 1 % to 3% In their ectopic path of eruption, they can cause damage (resorption) of the adjacent roots, a severe complication that may lead to the loss of anterior teeth. When cone-beam computed tomography (CT) scanning is used for diagnose, root resorption is detected in two-thirds of the lateral incisors adjacent to impacted maxillary canines before treatment. The treatment of this condition comprises two stages: a surgical intervention to uncover the canine crown followed by orthodontic treatment to move the canine into correct position. The surgical intervention commonly involves two different techniques: the open and the closed technique. The open technique procedure involves removing the bone and mucosa covering the crown of the canine. The exposed crown is left uncovered and a pack is placed over the area to avoid overgrowth of tissue. When enough spontaneous eruption of the canine has occurred, an orthodontic attachment is bonded to the crown and the tooth is moved above the mucosa with orthodontic appliances into the correct position. The closed technique procedure involves bonding an orthodontic attachment to the crown with a chain after exposing the canine during the surgery. The palatal flap is sutured back covering the exposed crown and the chain is left through the palatal mucosa free in the oral cavity. Shortly after, the canine is forced to erupt through the palatal mucosa and moved into the correct position with orthodontic appliances. The purpose of this prospective randomized clinical trial is to compare outcome variables between the Open and Closed surgical exposure techniques regarding the success of treatment, patient's perceptions of pain and discomfort experienced and analgesic consumption, treatment time, and complications. The null hypothesis is that similar outcomes occur when the surgical exposure of palatally impacted canines is performed by using the open or the closed surgical technique.

NCT ID: NCT04812860 Active, not recruiting - Clinical trials for Moderate to Severe Acute Pain

A Study to Evaluate the Efficacy and Safety of HR18042 Tablets in the Treatment of Postoperative Pain of Impacted Tooth.

Start date: December 8, 2020
Phase: Phase 2
Study type: Interventional

The purpose of this study was to evaluate the Efficacy and safety of HR18042 tablets for the Treatment of Post-surgical Pain After extraction of impacted tooth, find the optimal dose.

NCT ID: NCT04376268 Active, not recruiting - Clinical trials for Impacted Third Molar Tooth

Comparison of the Efficacy of Boric Acid Mouthwashes in Different Concentrations

Start date: January 15, 2019
Phase: Phase 4
Study type: Interventional

Surgical removal of impacted third molars is one of the most frequent procedures carried out in the oral and maxillofacial surgery clinics. There are a varying range of postoperative complications including pain, edema and swelling. Antibiotics, analgesics and mouthwashes are usually prescribed for the treatment of these complications. Patients undergoing impacted third molar surgery are frequently prescribed chlorhexidine mouthwashes with/without benzydamine hydrochloride. However, there has been a search for alternatives with anti-inflammatory, antibacterial and analgesic properties as part of the oral care routine following surgical removal of impacted third molars. Thus, this multicenter study was aimed to evaluate the effects of chlorhexidine mouthwashes with different boric acid concentrations (%0.1, %0.5, %1, %1.5, %2 and %2.5), and boric acid mouthwash on the postoperative complications and compared with chlorhexidine mouthwash after the removal of impacted wisdom teeth.

NCT ID: NCT04365088 Active, not recruiting - Clinical trials for Impacted Third Molar Tooth

Evaluation of the Effects of Pre-operative Deflazacort on Post-operative Pain, Edema and Trismus

Start date: December 15, 2018
Phase: Phase 4
Study type: Interventional

Removal of impacted lower third molar teeth is one of the most common oral surgical procedures, and these operations often lead to various complications in patients. Antibiotics, analgesics and/or anti-inflammatory drugs are prescribed for the treatment of complications encountered. Anti-inflammatory is the property of a substance or treatment that reduces inflammation or swelling. Anti-inflammatory drugs make up about half of analgesics, remedying pain by reducing inflammation as opposed to opioids, which affect the central nervous system to block pain signaling to the brain. Based on this information, in this study, it is aimed to evaluate the effects of deflazacort preoperatively on the postoperative pain, swelling and trismus.

NCT ID: NCT04349579 Active, not recruiting - Clinical trials for Impacted Third Molar Tooth

Evaluation of the Effects of Irrigation of the Extraction Socket With Rifamycine

Start date: November 15, 2018
Phase: Phase 4
Study type: Interventional

Removal of impacted lower third molar teeth is one of the most common oral surgical procedures, and these operations often lead to various complications in patients. Antibiotics, analgesics and mouthwashes are prescribed for the treatment of complications encountered. When using postoperative antibiotics in surgery of impacted third molar teeth, lower surgical area infection, pain, swelling and trismus are seen. Based on this information, in this study, it is aimed to evaluate the effects of rifamycine intraoperatively on the postoperative pain, swelling and trismus.

NCT ID: NCT03357484 Active, not recruiting - Pain Clinical Trials

Leukocyte- and Platelet Rich Fibrin (L-PRF) Application in Impacted Mandibular Third Molar Removal Surgery

Start date: March 1, 2017
Phase: N/A
Study type: Interventional

The purpose of this study was to evaluate the influence of leukocyte- and platelet-rich fibrin (L-PRF) on impacted mandibular third molar (IMTM) extraction wound healing, patient postoperative discomfort, and incidence of alveolar osteitis (AO). Thirty patients (18 female, 12 male) who met the inclusion criteria for this split-mouth study underwent bilateral IMTM surgical extractions. Following extraction, randomization was done. One socket received L-PRF, and the other socket served as a regular blood clot control. Postoperatively, the soft tissue healing index (HI), pain according to visual analog scale (VAS), facial swelling using a horizontal and vertical guide, and incidence of AO were evaluated 1, 3, 7, and 14 days after surgery.

NCT ID: NCT03169127 Active, not recruiting - Pain Clinical Trials

Clinical Pharmacogenetic of Ibuprofen After Lower Third Molar Surgeries

Start date: April 1, 2016
Phase: Phase 4
Study type: Interventional

The present clinical trial randomized will be to assess the link between the different haplotypes of CYP2C8 and CYP2C9 genes and the clinical efficacy of ibuprofen after lower third molar extractions. Onset, duration of postoperative analgesia, duration of anesthetic action on soft tissues, intraoperative bleeding, hemodynamic parameters, postoperative mouth opening and wound healing at the 7th postoperative day were evaluated. For this purpose, 200 healthy volunteers underwent removal of one lower third molar, under local anesthesia with articaine 4% (1:200,000 adrenaline) will be genotyped and phenotyped for these genes and their postoperative records with all data collected will be compared with the haplotypes found in the Brazilian population.

NCT ID: NCT02951676 Active, not recruiting - Clinical trials for Impacted Third Molar Tooth

Impact of Antibiotic Treatment and Extraction on the Oral Micro Biome

Start date: December 2015
Phase: N/A
Study type: Observational

This is a prospective, longitudinal, observational, cohort study investigating young adults undergoing surgical extraction of a wisdom tooth with and without antibiotics post-operatively. The prescription of antibiotics will be based on clinical judgment based on case complexity, trauma and length of procedure. No randomization will be performed. Saliva will be collected at seven observational time points ( Baseline, one week ,two weeks, three weeks , one month,three months and six months.) and Supragingival plaque samples will be collected at four observational time points ( Baseline , one week , one month, and 3 months) .A control group of 15 subjects who do not undergo dental extractions or antibiotic treatment will be recruited after obtaining informed consent and will be followed up for the same seven time points..Routine standard care will be observed. No new medications are triedThe samples will be analysed for identification of bacterial genes using 16 S r RNA gene sequecing and QPCR for change in the antibiotic resistance genes overtime. Kindly note that in the current study the participants are patients who are already scheduled to undergo tooth extractions with or without antibiotic treatment based on clinical judgement by the clinician performing the extraction. ( These patients are on the waiting list for third molar extractions in the dental hospital concerned.) The participants will receive the intervention( Third molar extraction with /without antibiotics) in the same manner and intensity even if they are not enrolled for the study.