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Changes in Biomarker of Exposure in Adults Who Smoke Cigarettes Switching From Cigarettes to Heated Tobacco Products

Tobacco Use Clinical Trial

Official title:
A Multi-site, Open-Label, Parallel-Group Study To Evaluate Changes In Tobacco-Related Biomarkers of Exposure and Biomarkers of Potential Harm With Use of Heated Tobacco Products Compared to Combustible Cigarettes in Adult Smokers

Clinical Trial Summary

The purpose of the study is to evaluate changes in biomarkers of exposure (BoE) to harmful and potentially harmful constituents (HPHCs) in adult smokers who completely switch to Ploom heated tobacco products (HTPs) compared to those who continue to smoke usual brand combustible cigarettes (UBCC).

Clinical Trial Description

This is a multi-site, open-label, two-group (menthol and non-menthol), six-arm (HTP, Continue Smoking, and Smoking Abstinence arms within each group) randomized, clinical study to evaluate changes in BoEs in adult smokers who remain smoking, switch to the Ploom HTP, or abstain from smoking, for 60 days (5 days in clinic followed by a 55-day ambulatory phase). Target enrollment is 300 male and female adult smokers between the ages of 22 and 65 in overall good health. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06179290
Study type Interventional
Source Altria Client Services LLC
Contact Jeffery S Edmiston, PhD
Phone 804 335-2366
Email Jeffery.S.Edmiston@altria.com
Status Recruiting
Phase N/A
Start date October 2, 2023
Completion date November 19, 2024
View Details
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