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Tissue Adhesions clinical trials

View clinical trials related to Tissue Adhesions.

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NCT ID: NCT05106400 Completed - Healthy Clinical Trials

Clinical Adhesion Study Between ZTlido 1.8% and Three Over-the-counter External Analgesic Lidocaine-containing Patches

Start date: July 1, 2021
Phase: Phase 1
Study type: Interventional

The study is designed to evaluate and compare the clinical adhesion performance of the ZTlido (Lidocaine Topical System) 1.8% of Scilex Pharmaceuticals Inc. (Reference) versus Salonpas (Lidocaine Patch 4%), Aspercreme (Lidocaine Patch 4%) and IcyHot (Lidocaine 4% + Menthol 1% Patch), on the Mid to upper back while being worn for 12 hours in healthy adult human subjects.

NCT ID: NCT05058027 Completed - Clinical trials for Tissue Adhesion, Surgery-Induced

Anti-adhesive Effect and Safety of MEDICURTAIN Applied to Undergoing Thyroid Surgery (Pivotal Study)

Start date: July 4, 2013
Phase: N/A
Study type: Interventional

This study was designed to demonstrate the non-inferiority of MEDICURTAIN® (investigational device) compared to commercially available GUARDIX-SG® (control device) in treatment of subject who underwent total thyroidectomy for prevention of adhesion formation at 6 weeks after the surgery.

NCT ID: NCT05049434 Completed - Sinusitis Clinical Trials

Efficacy and Safety for Medicurtain® in Prevention of Adhesion After Endoscopic Sinus Surgery (Pivotal Study)

Start date: March 3, 2014
Phase: N/A
Study type: Interventional

This clinical trial is to prove that the treatment group of Medicurtain® is non-inferior to the treatment group of Guardix-sol®, test equipment on adhesion after endoscopic sinus surgery, upon the aspects of adhesion prevention efficacy and safety.

NCT ID: NCT05036525 Completed - Thyroid Diseases Clinical Trials

Evaluation of the Efficacy and Safety of a Hyaluronic Acid Gel in Adhesion Prevention After Open Thyroidectomy.

Start date: June 17, 2022
Phase: N/A
Study type: Interventional

The aim of this study is to assess the safety and efficacy of HANBIO BarriGel to prevent thyroidectomy postoperative adhesions

NCT ID: NCT05027646 Completed - Healthy Volunteers Clinical Trials

Study to Assess Bioequivalence and Adhesion Properties Between Two Granisetron Transdermal Patches.

Start date: July 6, 2021
Phase: Phase 1
Study type: Interventional

The study is designed to evaluate the BE and adhesion properties of granisetron transdermal patches manufactured at 2 different sites. The study has been designed in accordance with the FDA Guidance for Industry. Bioequivalence will be based on the Cmax and AUC to determine the peak and total drug exposure, respectively.

NCT ID: NCT04848103 Completed - Pain, Postoperative Clinical Trials

Effect of Extracorporeal Shock Wave Therapy After Arthroscopic Rotator Cuff Repair

Start date: May 10, 2021
Phase: N/A
Study type: Interventional

Although radial extracorporeal shock wave therapy (rESWT) has proven to be an effective treatment, the effectiveness of the treatment has so far been controversial. There are no studies using rESWT in rehabilitation after arthroscopic rotator cuff repair (ARCR). Therefore, in this study, there is evidence that rESWT promotes pain control and healing recovery, and through previous studies, we would like to investigate whether treatment with rESWT during the intensive rehabilitation period of patients after ARCR is more effective in controlling pain.

NCT ID: NCT04824430 Completed - Clinical trials for Intrauterine Adhesion

Assessment of Uterine Access, Uterine Patency and Intrauterine Adhesions Following Endometrial Ablation

Start date: March 23, 2021
Phase:
Study type: Observational

The objective of this study is to gain information concerning the acute and longer-term morphological changes within the uterus following endometrial ablation. Hysteroscopic evaluation of the uterine cavity will be used to determine if physical access and the ability to systematically assess the post-ablation uterine cavity were preserved. The presence, location and severity of intrauterine adhesions will be documented in participants who are 3, 6 and 12 months from their standard of care endometrial ablation.

NCT ID: NCT04802889 Completed - Clinical trials for Vitreoretinal Detachment

Microarchitecture of Vitreoretinal Contact

Start date: January 1, 2008
Phase: N/A
Study type: Interventional

Investigation of the vitreoretinal contact microarchitecture in the macular and paramacular zones of the human retina.

NCT ID: NCT04784728 Completed - Healthy Clinical Trials

Pharmacokinetics and Adhesion of Lidocaine Topical System 1.8% With Water Exposure

Start date: August 21, 2019
Phase: Phase 1
Study type: Interventional

The objectives of this study are to evaluate the adhesion performance and pharmacokinetics of ZTlido (lidocaine topical system) 1.8% during swimming, showering, and under normal conditions.

NCT ID: NCT04688281 Completed - Clinical trials for Tissue Adhesion, Surgery-Induced

Spine Surgery for Adhesions in Patients Evaluated for Efficacy and Safety of MedicurtainⓇ (Pivotal Study)

Start date: October 11, 2011
Phase: N/A
Study type: Interventional

This study was designed to evaluate the efficacy and safety of Medicurtain®, an antiadhesion barrier in patients who underwent In Situ Decompression for single level and unilateral herniated lumbar intervertebral disc. Subjects were randomly assigned either into Medicurtain® treatment group or control group. Adhesion formations between the two groups at 12 weeks after surgery were compared by using MRI-applied scar score, ODI (Oswestry Disability Index) and VAS.