Clinical Trials Logo

Tissue Adhesions clinical trials

View clinical trials related to Tissue Adhesions.

Filter by:

NCT ID: NCT02847676 Not yet recruiting - Clinical trials for Peritoneal Adhesions

Differences in Peritoneal Stem Cells in Women With and Without Adhesions After Gynaecological Surgery

Start date: August 2016
Phase: N/A
Study type: Observational [Patient Registry]

Our study aims to characterise a possible pluripotent cell population in the abdomen responsible for peritoneal adhesions. We therefore want to take samples from women undergoing planned laparoscopic surgery with and without adhesions, isolate the cells and characterise them for markers of pluripotency.

NCT ID: NCT02836626 Active, not recruiting - Cesarean Section Clinical Trials

Fascial Scar Mobilization Techniques in Treating Chronic Caesarian Section Scar Pain

Start date: June 2016
Phase: N/A
Study type: Interventional

Over 1.37 million Caesarian sections (C-sections) are performed annually in the US . It is estimated that 12-20 % of those will result in chronic scar pain. This pain can lead to functional difficulties performing activities of daily living, pain with bowel movements, and pain with sexual activity . There is anecdotal evidence supporting the use of deep fascial scar mobilization techniques in reducing abdominal surgical scar pain, and yet almost no research has been published. The aims of this randomized clinical trial will be to determine if deep fascial scar mobilization techniques or superficial scar mobilization techniques will improve chronic pain and its resulting functional deficits, threshold pressure discomfort, pressure tolerance and mobility restrictions resulting from C-section surgery and to see if these interventions are more effective than no intervention. A positive result may result in an increase in the use of this intervention and thus the reduction of chronic scar pain for many women; it may provide justification for insurance reimbursement for this approach and it will also pave the way for further investigation into the use of these techniques with other types of painful scars including hysterectomy.

NCT ID: NCT02836470 Completed - Ileus Clinical Trials

A Study to Evaluate LB1148 for Return of Gastrointestinal Function and Adhesions in Subjects Undergoing Bowel Resection

PROFILE
Start date: October 1, 2019
Phase: Phase 2
Study type: Interventional

The purpose of this study is to establish preliminary evidence of the efficacy, safety, and tolerability of LB1148 for the treatment of post-operative ileus and intra-abdominal adhesions in subjects undergoing elective bowel resection.

NCT ID: NCT02790177 Not yet recruiting - Clinical trials for Post Operative Adhesions

Role of Hyaluronic Acid in the Prevention of Post-operative Adhesions: a RCT

HiB
Start date: June 2016
Phase: Phase 3
Study type: Interventional

The objective of study is to determine the effect of hyaluronic acid on the formation of post-operative adhesions. It will be a randomized control trial comparing the product against normal saline.

NCT ID: NCT02773251 Completed - Prostate Cancer Clinical Trials

The Effect of Guardix-solution for the Prevention of Postoperative Intestinal Adhesion and Intestinal Obstruction After Laparoscopic Pelvic Cavity Surgery: Randomized, Prospective, Multicenter Study

Start date: November 2011
Phase: Phase 4
Study type: Interventional

To assess the anti-adhesive effect of treatment with hyaluronic acid-carboxymethylcellulose following laparoscopic pelvic surgery (radical prostatectomy).

NCT ID: NCT02744807 Completed - Clinical trials for Intrauterine Adhesions

Role of Chronic Endometritis in Postoperative Recurrence of Severe Intrauterine Adhesions

Start date: May 2015
Phase: N/A
Study type: Observational

This study is to evaluate the prevalence of chronic endometritis (CE) in women with severe intrauterine adhesions and compare recurrence of adhesion in women with and without CE.

NCT ID: NCT02744716 Completed - Clinical trials for Intrauterine Adhesion

Effects of Aspirin on Uterine Endometrial Repair Severe Intrauterine Adhesion

Start date: May 2011
Phase: N/A
Study type: Interventional

This study aimed To investigate the effects of estrogen in combination with aspirin and intrauterine balloon on the uterine endometrial repair and reproductive prognosis in patients after surgery for severe intrauterine adhesion .

NCT ID: NCT02726971 Completed - Asherman Syndrome Clinical Trials

Comparison of Different Doses of Oestrogen Therapy for Preventing Intrauterine Adhesion

Start date: April 2016
Phase: Phase 1/Phase 2
Study type: Interventional

This single-center,prospective,randomized,controlled trial is conducted to evaluate the efficacy of different doses of estrogen artificial periodic therapy after hysteroscopic adhesiolysis in patients with moderate-severe adhesion.

NCT ID: NCT02617108 Not yet recruiting - Uterine Septum Clinical Trials

Intrauterine Balloon and Postoperative Estrogen Therapy in the Prevention of Adhesion Reformation After Hysteroscopic Adhesiolysis

Start date: December 2019
Phase: N/A
Study type: Interventional

Patients who want to go TCRS will randomly divided 3 groups. In Group 1(100 patients), women received postoperative estrogen therapy. In Group 2 (100 patients), a Foley catheter with the balloon inflated with 4 ml of normal saline solution will be placed into the uterine cavity at the end of the operation for five days. In Group 3 (110 patients), women will not receive any of the treatment (comparison group). All subjects underwent two further hysteroscopy, one and three months after the initial surgery. At the second or third look hysteroscopy, the incidence of intra-uterine adhesion will be analyzed.

NCT ID: NCT02612818 Active, not recruiting - Clinical trials for Endometriosis, Adhesive

Prevention of Adhesions During Celioscopy for Endometriosis. Impact of the Use of Anti-adhesion Treatment on Clinical Signs and Fertility at One Year

ENDHY
Start date: November 24, 2015
Phase:
Study type: Observational

Thus is a longitudinal, prospective, multicentric observational study performed in mainland France, among a sample of gynaecology surgeons practising at endometriosis "expert" centres. The aim of this study is to describe, under real treatment conditions in patients suffering from endometriosis, the impact of the use of anti-adhesion treatment during celioscopy surgery on the development of clinical signs in the patients and their fertility at one year.