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Thyroid Cancer clinical trials

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NCT ID: NCT04133870 Active, not recruiting - Thyroid Cancer Clinical Trials

Identification of Molecular Biomarkers for Thyroid Cancer

Start date: December 21, 2015
Phase:
Study type: Observational

This is a two part study; part A proposes to collect plasma samples to examine how ctDNA (circulating thyroid DNA) markers correlate with detection of recurrent disease, response to therapy, clinical outcome and pathological data. Part B aims to use tissue obtained from biopsies of primary or recurrent disease to establish cell lines and tumour explants to further investigate the biology of thyroid cancer in the preclinical setting

NCT ID: NCT04000880 Active, not recruiting - Breast Cancer Clinical Trials

Adapting Multiple Behavior Interventions That Effectively Improve Cancer Survivor Health Cancer Survivor Health

AMPLIFY
Start date: March 4, 2020
Phase: N/A
Study type: Interventional

This research study will test the efficacy of interactive, web-based interventions that improve diet, physical activity and weight management changes among early stage survivors of breast, prostate, colorectal, endometrial, renal, thyroid, and ovarian cancers, as well as multiple myeloma and non-Hodgkin Lymphoma. Overarching outcomes also include physical function and performance, muscle mass, quality of life, and health utilities.

NCT ID: NCT03484884 Active, not recruiting - Thyroid Cancer Clinical Trials

A Study of Optical Imaging With Light From Radiotracers in Cancer Patients

Start date: March 20, 2018
Phase:
Study type: Observational

The purpose of this study is to test Cerenkov luminescence imaging, which is a different way to take pictures of thyroid cancer and/or any tumors with (existing or suspected) nodal metastases in the neck, supraclavicular, axillary and/or inguinal region.

NCT ID: NCT03345563 Active, not recruiting - Prostate Cancer Clinical Trials

Project HERO: Health Empowerment & Recovery Outcomes

HERO
Start date: July 19, 2019
Phase: N/A
Study type: Interventional

Project HERO is a 12-week study of the efficacy of Body Mind Training (BMT) for reducing fatigue in male cancer survivors. This 3-arm randomized clinical trial will examine inflammatory biology and selected gene-expression pathways that are hypothesized to contribute to the intervention's effect.

NCT ID: NCT03285230 Active, not recruiting - Breast Cancer Clinical Trials

The French E3N Prospective Cohort Study

E3N
Start date: June 15, 1990
Phase: N/A
Study type: Observational

The French E3N cohort was initiated in 1990 to investigate the risk factors associated with cancer and other major non-communicable diseases in women. The participants were insured through a national health system that primarily covered teachers, and were enrolled from 1990 after returning baseline self-administered questionnaires and providing informed consent. The cohort comprised nearly 100 000 women with baseline ages ranging from 40 to 65 years. Follow-up questionnaires were sent approximately every 2-3 years after the baseline and addressed general and lifestyle characteristics together with medical events (cancer, cardiovascular diseases, diabetes, depression, fractures and asthma, among others). The follow-up questionnaire response rate remained stable at approximately 80%. A biological material bank was generated and included blood samples collected from 25 000 women and saliva samples from an additional 47 000 women. Ageing among the E3N cohort provided the opportunity to investigate factors related to agerelated diseases and conditions as well as disease survival.

NCT ID: NCT03246958 Active, not recruiting - Thyroid Cancer Clinical Trials

Nivolumab Plus Ipilimumab in Thyroid Cancer

Start date: September 20, 2017
Phase: Phase 2
Study type: Interventional

This research study is studying nivolumab, an investigational drug, in combination with ipilimumab, also an investigational drug, as a possible treatment for thyroid cancer. The drugs involved in this study are: - Nivolumab (Opdivo™) - Ipilimumab (Yervoy™)

NCT ID: NCT03215095 Active, not recruiting - Thyroid Cancer Clinical Trials

RAI Plus Immunotherapy for Recurrent/Metastatic Thyroid Cancers

Start date: July 10, 2017
Phase: Early Phase 1
Study type: Interventional

The purpose of this study is to find out what effects, good and/or bad, a drug called durvalumab combined with Thyrogen-stimulated RAI, has on the patient and thyroid cancer. Durvalumab is a drug that has been developed to activate the immune system by blocking a protein called programmed death ligand-1 (PD-L1) that can be present on tumor and normal cells, including immune cells.

NCT ID: NCT03196518 Active, not recruiting - Thyroid Cancer Clinical Trials

Study of PET Imaging With 18F-TFB in Patients With Thyroid Cancer

Start date: June 16, 2017
Phase: N/A
Study type: Interventional

The goal of the study is to evaluate a new imaging test that may allows the investigators to predict the uptake of radioactive iodine by thyroid cancer faster than the current standard and that does not interfere with the uptake of radioactive iodine used for therapy.

NCT ID: NCT02953288 Active, not recruiting - Thyroid Cancer Clinical Trials

Differential Diagnosis and Clinical Treatment Strategies of Thyroid Nodules.

Start date: October 2016
Phase: N/A
Study type: Observational

To investigate the genetic mutations of patients with thyroid carcinoma and find molecular targets for therapy.

NCT ID: NCT02938702 Active, not recruiting - Thyroid Cancer Clinical Trials

Active Surveillance on Papillary Thyroid Microcarcinoma

Start date: May 2016
Phase:
Study type: Observational

The study is a multi-center prospective cohort study of active surveillance in papillary thyroid cancer with low risk. The purpose of the study is to observe natural course of low risk papillary thyroid cancer in Korean population, and comparison of prognosis between active surveillance group and conventional surgery group. Patient will be well informed about their choice of active surveillance or surgery.