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Thoracic Surgery, Video-Assisted clinical trials

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NCT ID: NCT04929665 Completed - Pain, Postoperative Clinical Trials

Thoracic Paravertebral Block, Erector Spinae Plane Block, and in Combined Paravertebral-erector Spinae Block

Start date: April 1, 2021
Phase: N/A
Study type: Interventional

Video-assisted thoracic surgery (VATS) has become a common procedure in thoracic surgery. Severe postoperative pain may be encountered in patients undergoing VATS. Analgesic methods such as thoracic paravertebral block (TPVB), intercostal block and erector spina plane block (ESPB) are widely used for VATS. Among these methods, ultrasound (US) guided TPVB is the most preferred method. Generally, comparisons are made between ESPB and TPVB in studies and the analgesic effect is evaluated. However, no research could be found in the literature combining ESPB and TPVB. The mechanisms of regional analgesia techniques used after thoracic surgery operations are also different from each other. Therefore, it may be possible to obtain a more effective analgesic effect in patients by combining the mechanism of action of TPVB and ESPB, as in the multimodal analgesia method. This study seeks to evaluate the effect of TPVB, ESPB and combined TPVB-ESPB pain after VATS.

NCT ID: NCT04665531 Completed - Clinical trials for Thoracic Surgery, Video-Assisted

Postoperative Analgesia With a Catheter Under the Erector Spinae Muscle for Videothoracoscopic Lung Surgery

ESCAV
Start date: February 19, 2020
Phase: N/A
Study type: Interventional

The purpose of the research is to prove the analgesic efficacy of a novel technique in regional anaesthesia, i.e. the catheter under the erector spinae muscle (ESC). Investigators will evaluate the use of the ESC for analgesia after video-assisted thoracoscopic lung surgeries in comparison to the standard method of post-operative analgesia, which is the multiple level intercostal block given at the end of surgery by the surgeon. Investigators will compare the amount of opioid analgesics required by the patient using the patient controlled pump, the pain status in 48-hours after surgery and compare the differences between pre- and post-operative main inspiratory pressure and main expiratory pressure measurements between the two research groups.

NCT ID: NCT04511091 Completed - Clinical trials for Thoracic Surgery, Video-Assisted

Studio Osservazionale Retrospettivo Uneventful Vatslobectomy: Caratteristiche Cliniche All'Interno Del Registro Vats Group

VATS
Start date: January 1, 2014
Phase:
Study type: Observational

Background VATS lobectomy centers face pressure to reduce hospitalization to contain costs, and some centers have sought to develop "fast-track" protocols. There are limited data to identify which patients would be appropriate for fast-tracking. Objective The first objective was to identify factors associated to short lenght of stay after VATS lobectomy. The second objective was to verify the influence of these variables in uncomplicated VATS lobectomy. Methods We reviewed all thoracoscopic lobectomies for cancer operations reported to the Italian VATS Group between January 2014 and January 2020. Patient and procedural characteristics, length of stay and 30-day morbidity and mortality were reviewed. Patients were divided into two subgroups depending on their reaching the targeted length of stay (≤ or > 4 days). The association between preoperative and intraoperative variables and postoperative length of stay (LOS) ≤ 4 days was assessed using a stepwise multivariate logistic regression analysis to identify factors independently associated with LOS and factors related to LOS in uncomplicated cases.

NCT ID: NCT03916120 Completed - Pain, Postoperative Clinical Trials

Single Nucleotide Polymorphisms (SNPs) Associated With Postoperative Analgesic Failure

Start date: July 15, 2018
Phase:
Study type: Observational

Postoperative pain remains relatively high within 48h for Chinese patients who receive video-assisted thoracoscopic surgery. Different patients experience different pain intensity. This suggests that there may be genetic variants that make some patients susceptible to analgesic failure. Using blood samples from patients, the investigators are going to analyze the relationship between single nucleotide polymorphisms (SNPs) in genes that are known to be involved in analgesic failure.

NCT ID: NCT03860480 Completed - Clinical trials for Thoracic Surgery, Video-Assisted

Erector Spinae Plane Block For Analgesia Following Video-Assisted Thoracoscopic Surgery

Start date: November 29, 2018
Phase: N/A
Study type: Interventional

Erector spinae (ESP) block is a recently described plane block designed to block the dorsal and ventral rami of the thoracic spinal nerves. It is meant to block the ipsilateral trunk. The aim of the study is to demonstrate the efficacy of the ESP block as postoperative analgesia for VATS surgery.

NCT ID: NCT03648008 Completed - Pain, Postoperative Clinical Trials

Postoperative Analgesic Effect of Hydromorphone on Partial Pulmonary Resection Under Video-assisted Thoracoscopy

Start date: May 5, 2018
Phase: Phase 4
Study type: Interventional

Postoperative pain remains relatively high within 48h for Chinese patients who receive video-assisted thoracoscopic surgery. Multimodal analgesia combines several agents and/or techniques to function on diverse nociceptive mechanisms to enhance pain relief and lessen side effect. Hydromorphone is a hydrogenated ketone of morphine and approximately 5-10 times more potent. There lacks about efficacy and efficiency of hydromorphone in electrical pump for patient controlled intravenous analgesic (PCIA).

NCT ID: NCT03296449 Completed - Clinical trials for One-Lung Ventilation

Comparison Between CPAP and HFJV During One-lung Ventilation in VATS

Start date: November 22, 2017
Phase: N/A
Study type: Interventional

This study compares two ventilatory techniques (continuous positive airway pressure vs high frequency jet ventilation) during one-lung ventilation (OLV) in video-assisted thoracic surgery (VATS). All patients were ventilated with both ventilatory techniques and parameters of gas exchange were determined through arterial blood gas test.

NCT ID: NCT02952261 Completed - Lung Neoplasm Clinical Trials

Application of 3D Printing Technique in Small Pulmonary Nodule Localization

Start date: October 24, 2016
Phase: N/A
Study type: Interventional

The trial is to evaluate the efficacy and safety of three-dimensional printed navigational template in the clinical application of small peripheral lung nodule localization.

NCT ID: NCT01068457 Completed - Chronic Pain Clinical Trials

Chronic Pain After Thoracotomy (Video Assisted Thoracic Surgery - VATS)

Start date: December 2009
Phase: N/A
Study type: Observational

This is an explorative study investigating potential nerve injury after VATS.