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NCT03402191 Clinical Trial

L-arginine Versus Sildenafil in Children With Beta Thalassemia Associated With Pulmonary Hypertension

Thalassemia Clinical Trial

Official title:
Comparative Clinical Study Evaluating the Effect of L-arginine Versus Sildenafil in Children With Beta Thalassemia Associated With Pulmonary Hypertension

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT03402191
Other study ID # Prof Elshanshoury
Secondary ID
Status Recruiting
Phase Phase 4
First received
Last updated
Start date July 2016
Est. completion date December 2023

Study information
Verified date August 2018
Source Tanta University
Contact Sherief Abd-Elsalam, MD
Phone 00201095159522
Email sheriefabdelsalam@yahoo.com
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

This study compares L-arginine Versus Sildenafil as treatment for pulmonary hypertension in Children with Beta Thalassemia

Description:

This study focuses on different lines of treatment for pulmonary hypertension in children with thalassemia as this study discusses the Effect of L-arginine Versus Sildenafil in Children with Beta Thalassemia Associated with Pulmonary Hypertension

Recruitment information / eligibility
Status Recruiting
Enrollment 60
Est. completion date December 2023
Est. primary completion date December 2023
Accepts healthy volunteers No
Gender All
Age group 6 Years to 18 Years
Eligibility Inclusion Criteria:

- Children with thalassemia and pulmonary hypertension.

Exclusion Criteria:

- Rheumatic heart diseases.

- Other comorbid disease

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• L-arginine
l-arginine for thalassemia with pulmonary hypertension
• Sildenafil
Sildenafil for thalassemia with pulmonary hypertension

Locations
Country Name City State
Egypt Sherief Abd-Elsalam Tanta

Sponsors (1)
Lead Sponsor Collaborator
Sherief Abd-Elsalam

Country where clinical trial is conducted

Egypt, 

Outcome
Type Measure Description Time frame Safety issue
Primary Number of patients with improvement of pulmonary hypertension patients with improvement of pulmonary hypertension 6 months
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